50-199-0571

Phospho-Pdcd4 (Ser457)Mouse anti-Human, Mouse, Rat, Xenopus laevis, Clone: 9G6, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-0571-Each-of-1 In Stock ₹ 2,42,839.81

50-199-0571 - Each of 1

₹ 2,42,839.81

In Stock

Quantity

1

Base Price: ₹ 2,42,839.81

GST (18%): ₹ 43,711.166

Total Price: ₹ 2,86,550.976

Antigen

Phospho-Pdcd4 (Ser457)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q53EL6, Q61823, Q9JID1

Gene Symbols

PDCD4

Immunogen

Anti-Pdcd4 phospho S457 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein.

Regulatory Status

RUO

Gene ID (Entrez)

18569, 27250, 64031

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

9G6

Conjugate

Unconjugated

Gene

PDCD4

Gene Alias

D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species

Mouse

Quantity

1 mg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat, X. laevis

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for human Pdcd4 protein phosphorylated at Ser457
  • A BLAST analysis was used to suggest cross-reactivity with Pdcd4 from human, mouse, rat and Xenopus based on 100% homology with the immunizing sequence
  • Cross-reactivity with Pdcd4 from other sources has not been determined
  • Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
  • During this process, the expression patterns of numerous genes are radically altered
  • One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis
  • PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate
  • It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1
  • The kinase Akt regulates PDCD4 by phosphorylation, decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun
  • There are two known isoforms of PDCD4.

Compare Similar Items

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Rockland Immunochemicals

50-199-0571

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Antigen:
Phospho-Pdcd4 (Ser457)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q53EL6, Q61823, Q9JID1

Gene Symbols:
PDCD4

Immunogen:
Anti-Pdcd4 phospho S457 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein.

Regulatory Status:
RUO

Gene ID (Entrez):
18569, 27250, 64031

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
9G6

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species:
Mouse

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Rockland Immunochemicals

50-199-0572

--


Antigen:
Phospho-Stat5 (Ser694)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P42229, P42230, Q62771

Gene Symbols:
STAT5A

Immunogen:
Phospho STAT5 pY694 monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5a protein.

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 24918, 6776

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
5F6.F1

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963; BOS_19069; Mammary gland factor; mammary gland factor STAT5A; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5A; STAT; STAT5; Stat5a; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species:
Mouse

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Rockland Immunochemicals

50-199-0575

--


Antigen:
AKT

Classification:
Monoclonal

Concentration:
__

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P31749, P31750, P31751, P47196, P47197, Q60823, Q63484, Q9WUA6, Q9Y243

Gene Symbols:
AKT1, Akt2, Akt3

Immunogen:
Anti-Akt monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues near the C terminal end of human AKT1 protein.

Regulatory Status:
RUO

Gene ID (Entrez):
10000, 100609583, 11651, 11652, 207, 208, 23797, 24185, 25233, 29414, 456035, 740898

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
2410016A19Rik; AI851531; Akt; Akt kinase; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT serine/threonine kinase 3; AKT/PKB; Akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; AKT2; AKT2 kinase; Akt3; AKT3 kinase; akt3a; AW554154; cb945; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; D930002M15Rik; DAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; dAkt1; DAKT1/PKB; DKFZp434N0250; Dmel\CG4006; Dmel_CG4006; Dpkb; DRAC-PK; DRAC-PK66; DRAC-PK85; HIHGHH; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; MPPH; MPPH2; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 1; murine thymoma viral (v-akt) oncogene homolog 2; Nmf350; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/Akt; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBB; PKBbeta; PKBG; PKB-GAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B alpha; Protein kinase B beta; Protein kinase B gamma; protein kinase B, beta; protein kinase B, gamma; protein kinase B-alpha; Proto-oncogene c-Akt; putative v-akt murine thymoma viral oncoprotein 2; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; serine-threonine protein kinase; si:ch211-221n23.2; STK-2; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; thymoma viral proto-oncogene 2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 1; v-akt murine thymoma viral oncogene-like 3; v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Mouse

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Chimpanzee, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-199-0576

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Antigen:
LGR4

Classification:
Monoclonal

Concentration:
1.13 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q9BXB1

Gene Symbols:
LGR4

Immunogen:
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.

Regulatory Status:
RUO

Gene ID (Entrez):
451088, 55366, 701736

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
6G8.B3.G5.C3

Conjugate:
Unconjugated

Gene:
LGR4

Gene Alias:
9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; G protein-coupled receptor 48; G protein-coupled receptor GPR48; GPR48; G-protein coupled receptor 48; leucine rich repeat containing G protein-coupled receptor 4; leucine-rich repeat containing G protein-coupled receptor 4; leucine-rich repeat-containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4; LGR4

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chimpanzee, Human, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2b κ