50-199-1724

PDK1Rabbit anti-Human, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1724-Each-of-1 In Stock ₹ 50,884.24

50-199-1724 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

PDK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDK1

Gene Alias

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

5163

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1.3 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q15118

Gene Symbols

PDK1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Directed against human PDK-1
  • A BLAST analysis was used to suggest cross-reactivity with PDK-1 protein from mouse, rat and dog based on 92% homology with the immunizing sequence
  • Reactivity against homologues from other sources is unknown
  • Serine/threonine kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2
  • This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate
  • Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia
  • Protects cells against apoptosis in response to hypoxia and oxidative stress.

Compare Similar Items

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Img

Rockland Immunochemicals

50-199-1724

--


Antigen:
PDK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDK1

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
5163

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1.3 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q15118

Gene Symbols:
PDK1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1725

--


Antigen:
Caspase-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP2

Gene Alias:
Casp2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; Caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; Ich1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; Nedd2; Nedd-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
12366, 64314

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
0.44 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P29594, P55215

Gene Symbols:
CASP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1726

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Antigen:
Phospho-PAK 1/2/3 (Thr423)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pak1

Gene Alias:
activated protein kinase alpha; ADRB2; Alpha-PAK; AW045634; CDC42/RAC effector kinase PAK-A; EC 2.7.11.1; kinase PAK1; MGC130000; MGC130001; p21 (CDKN1A)-activated kinase 1; p21 (RAC1) activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p65-PAK; p68-PAK; PAK 1; Pak1; PAK-1; PAK1B; Paka; PAKalpha; Protein kinase MUK2; Serine/threonine-protein kinase PAK 1; STE20 homolog, yeast

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
5058

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q13153

Gene Symbols:
Pak1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1727

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Antigen:
Phospho-NF2 (Ser518)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nf2

Gene Alias:
ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; Moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); Neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; Schwannomin

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
18016, 4771

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P35240, P46662

Gene Symbols:
Nf2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody