50-199-1888

Pdcd4Rabbit anti-Human, Mouse, Rat, Xenopus laevis, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-1888-Each-of-1 In Stock ₹ 33,881.76

50-199-1888 - Each of 1

₹ 33,881.76

In Stock

Quantity

1

Base Price: ₹ 33,881.76

GST (18%): ₹ 6,098.717

Total Price: ₹ 39,980.477

Antigen

Pdcd4

Classification

Polyclonal

Formulation

0.02M potassium phosphate with 0.01% BSA, 0.15M NaCl, 25% glycerol and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q53EL6, Q61823, Q9JID1

Gene Symbols

PDCD4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat, X. laevis

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

PDCD4

Gene Alias

D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

18569, 27250, 64031

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Store vial at 2-8°C prior to opening
  • May aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • Dilute only prior to use
  • RTU Anti-Pdcd4 affinity purified antibody is directed against human Pdcd4 protein
  • A BLAST analysis was used to suggest cross-reactivity with Pdcd4 from human, mouse, rat and Xenopus based on 100% homology with the immunizing sequence
  • Cross-reactivity with Pdcd4 from other sources has not been determined
  • The antibody reacts with Pdcd4 protein that is either phosphorylated or non-phosphorylated at Ser457
  • Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
  • During this process, the expression patterns of numerous genes are radically altered
  • One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis
  • PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate
  • It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1
  • The kinase Akt regulates PDCD4 by phosphorylation, decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun
  • There are two known isoforms of PDCD4.

Compare Similar Items

Show Difference

Img

Rockland Immunochemicals

50-199-1888

--


Antigen:
Pdcd4

Classification:
Polyclonal

Formulation:
0.02M potassium phosphate with 0.01% BSA, 0.15M NaCl, 25% glycerol and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q53EL6, Q61823, Q9JID1

Gene Symbols:
PDCD4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
18569, 27250, 64031

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Rockland Immunochemicals

50-199-1889

--


Antigen:
Pdcd4

Classification:
Polyclonal

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q53EL6, Q61823, Q9JID1

Gene Symbols:
PDCD4

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
18569, 27250, 64031

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Bioworld

50-199-189

--


Antigen:
__

Classification:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Applications:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Rockland Immunochemicals

50-199-1890

--


Antigen:
DAXX

Classification:
Polyclonal

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O35613, Q8VIB2, Q9UER7

Gene Symbols:
DAXX

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Applications:
ELISA, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Gene:
DAXX

Gene Alias:
BING2; BOS_21285; CENP-C binding protein; DADB-159G18.9; DAP6; DAXX; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
13163, 140926, 1616

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid