50-199-2784
Histone H2A.X Polyclonal Antibody, Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2784-Each-of-1 | In Stock | ₹ 12,834.00 |
50-199-2784 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,834.00
GST (18%): ₹ 2,310.12
Total Price: ₹ 15,144.12
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3014
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Concentration
Lot-Specific
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.
P16104
Gene Symbols
H2AX
Immunogen
This Histone H2AX antibody was raised against a peptide derived from the C-terminus of human histone H2AX.
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Concentration: Lot-Specific
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: This Histone H2AX antibody was raised against a peptide derived from the C-terminus of human histone H2AX.
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Concentration:
Lot-Specific
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
This Histone H2AX antibody was raised against a peptide derived from the C-terminus of human histone H2AX.
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFkB p65 (Ser529)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RELA
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5970
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: Lot-Specific
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q04206
Gene Symbols: RELA
Immunogen: This NFkB p65 phospho Ser529 antibody was raised against a peptide containing phospho-serine 529 of human NFkB p65.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFkB p65 (Ser529)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RELA
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5970
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
Lot-Specific
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q04206
Gene Symbols:
RELA
Immunogen:
This NFkB p65 phospho Ser529 antibody was raised against a peptide containing phospho-serine 529 of human NFkB p65.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFkB p65 (Ser529)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RELA
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5970
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: Lot-Specific
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q04206
Gene Symbols: RELA
Immunogen: This NFkB p65 phospho Ser529 antibody was raised against a peptide containing phospho-serine 529 of human NFkB p65.
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFkB p65 (Ser529)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RELA
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5970
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
Lot-Specific
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q04206
Gene Symbols:
RELA
Immunogen:
This NFkB p65 phospho Ser529 antibody was raised against a peptide containing phospho-serine 529 of human NFkB p65.
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Mi-2 beta
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CHD4
Gene Alias: 9530019N15Rik; AA617397; ATP-dependent helicase CHD4; BC005710; CHD4; CHD-4; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; D6Ertd380e; Mi-2; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; MI2B; Mi-2b; Mi-2beta; Mi2-beta; mKIAA4075
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 107932, 1108
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q14839, Q6PDQ2
Gene Symbols: CHD4
Immunogen: This Mi-2 beta antibody was raised against a synthetic peptide derived from human Mi-2B.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Mi-2 beta
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CHD4
Gene Alias:
9530019N15Rik; AA617397; ATP-dependent helicase CHD4; BC005710; CHD4; CHD-4; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; D6Ertd380e; Mi-2; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; MI2B; Mi-2b; Mi-2beta; Mi2-beta; mKIAA4075
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
107932, 1108
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q14839, Q6PDQ2
Gene Symbols:
CHD4
Immunogen:
This Mi-2 beta antibody was raised against a synthetic peptide derived from human Mi-2B.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG