50-199-2857

5-Hydroxymethylcytosine (5-hmC) Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2857-Each-of-1 In Stock ₹ 11,807.28

50-199-2857 - Each of 1

₹ 11,807.28

In Stock

Quantity

1

Base Price: ₹ 11,807.28

GST (18%): ₹ 2,125.31

Total Price: ₹ 13,932.59

Antigen

5-Hydroxymethylcytosine (5-hmC)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2

Immunogen

This 5-Hydroxymethylcytidine antibody was raised against 5-hydroxymethylcytidine conjugated to kLH and recognizes 5-hydroxymethylcytosine.

Quantity

10 μg

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Dot Blot, Immunohistochemistry, Immunoprecipitation

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • 5-hydroxymethylcytosine (5-hmC) has been recently discovered in mammalian DNA
  • 5-hmC results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases
  • Initially, the 5-hmC base had been identified in Purkinje neurons, in granule cells and embryonic stem cells where it is present at high levels (up to 0,6% of total nucleotides in Purkinje cells)
  • A recent report indicates that 5-hmC is also abundant in brain tissue, especially in areas that are associated with higher cognitive functions.Early evidence suggests that 5-hmC may represent an intermediate in a new pathway which demethylates DNA, converting 5-mC to cytosine
  • Although its precise role has still to be shown, recent results indicate, however, that 5-hmC may play important roles distinct from 5-mC
  • This may open up entirely new perspectives in epigenetic studies.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-2857

--


Antigen:
5-Hydroxymethylcytosine (5-hmC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2

Immunogen:
This 5-Hydroxymethylcytidine antibody was raised against 5-hydroxymethylcytidine conjugated to kLH and recognizes 5-hydroxymethylcytosine.

Quantity:
10 μg

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, Immunohistochemistry, Immunoprecipitation

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2858

--


Antigen:
5-Hydroxymethylcytosine (5-hmC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2

Immunogen:
This 5-Hydroxymethylcytidine antibody was raised against 5-hydroxymethylcytidine conjugated to kLH and recognizes 5-hydroxymethylcytosine.

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, Immunohistochemistry, Immunoprecipitation

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2859

--


Antigen:
MEIS 1/2/3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
__

Immunogen:
This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

Fischer Scientific

50-199-2860

--


Antigen:
MEIS 1/2/3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
__

Immunogen:
This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Quantity:
10 μg

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1