50-199-4143

3-Methylcytosine (3-mC) Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-4143-Each-of-1 In Stock ₹ 46,441.97

50-199-4143 - Each of 1

₹ 46,441.97

In Stock

Quantity

1

Base Price: ₹ 46,441.97

GST (18%): ₹ 8,359.555

Total Price: ₹ 54,801.525

Antigen

3-Methylcytosine (3-mC)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3

Immunogen

This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .

Regulatory Status

RUO

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Dot Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • 3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM)
  • Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA
  • The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation
  • Therefore, it has to be repaired by the cell
  • This is established by oxidative demethylation, which is catalyzed by the AlkB protein.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-4143

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Antigen:
3-Methylcytosine (3-mC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3

Immunogen:
This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4144

--


Antigen:
3-Methylcytosine (3-mC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3

Immunogen:
This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4147

--


Antigen:
5-Carboxylcytosine (5-caC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
__

Immunogen:
This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Regulatory Status:
RUO

Target Species:
__

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4148

--


Antigen:
5-Carboxylcytosine (5-caC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
__

Immunogen:
This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Regulatory Status:
RUO

Target Species:
__

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid