50-227-7253

5-Carboxylcytosine (5-caC) Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-227-7253-Each-of-1 In Stock ₹ 26,694.72

50-227-7253 - Each of 1

₹ 26,694.72

In Stock

Quantity

1

Base Price: ₹ 26,694.72

GST (18%): ₹ 4,805.05

Total Price: ₹ 31,499.77

Antigen

5-Carboxylcytosine (5-caC)

Classification

Polyclonal

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Product Type

Antibody

Isotype

IgG

Applications

Dot Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Immunogen

This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Regulatory Status

RUO

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Target Molecule

Chemical

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Description

  • 5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation
  • 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine
  • These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family
  • 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II
  • Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.

Compare Similar Items

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Img

Fischer Scientific

50-227-7253

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Antigen:
5-Carboxylcytosine (5-caC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Immunogen:
This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Regulatory Status:
RUO

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Img

Fischer Scientific

50-227-7254

--


Antigen:
Histone H3ac (pan-acetyl)

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen:
This antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of human Histone H3.

Regulatory Status:
RUO

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Fischer Scientific

50-227-7256

--


Antigen:
CtIP

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen:
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Regulatory Status:
RUO

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Fischer Scientific

50-227-7261

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Antigen:
Phospho-RNA pol II CTD (Tyr1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Rat

Quantity:
50 μg

Primary or Secondary:
Primary

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen:
This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.

Regulatory Status:
RUO

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__