50-227-7256

CtIP Monoclonal Antibody (14-1), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-227-7256-Each-of-1 In Stock ₹ 29,261.52

50-227-7256 - Each of 1

₹ 29,261.52

In Stock

Quantity

1

Base Price: ₹ 29,261.52

GST (18%): ₹ 5,267.074

Total Price: ₹ 34,528.594

Antigen

CtIP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q99708

Gene Symbols

Rbbp8

Immunogen

This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

14-1

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5932

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

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Img

Fischer Scientific

50-227-7256

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Antigen:
CtIP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q99708

Gene Symbols:
Rbbp8

Immunogen:
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
14-1

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5932

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-227-7261

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Antigen:
Phospho-RNA pol II CTD (Tyr1)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
P24928

Gene Symbols:
POLR2A

Immunogen:
This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Clone:
3D12

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5430

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-227-7264

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Antigen:
N6-Methyladenosine (m6A)

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This antibody was raised against 6-Methyladenosine conjugated to kLH.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Multi-species, Rat, Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-227-7267

--


Antigen:
METTL1/WDR4

Classification:
Polyclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide

Gene Accession No.:
P57081, Q9UBP6

Gene Symbols:
__

Immunogen:
This antibody was raised against a human peptide containing methyltransferase 1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
METTL1

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10785, 4234

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid