50-199-3179

CtIP Monoclonal Antibody (14-1), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3179-Each-of-1 In Stock ₹ 12,834.00

50-199-3179 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

CtIP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q99708

Gene Symbols

Rbbp8

Immunogen

This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Quantity

10 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Clone

14-1

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5932

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

Compare Similar Items

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Img

Fischer Scientific

50-199-3179

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Antigen:
CtIP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q99708

Gene Symbols:
Rbbp8

Immunogen:
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Clone:
14-1

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5932

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3180

--


Antigen:
Mili / PiwiL2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8CDG1

Gene Symbols:
Piwil2

Immunogen:
This Mili / PiwiL2 antibody was raised against full-length recombinant mouse MILI / PIWIL2 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Clone:
17.8

Conjugate:
Unconjugated

Gene:
Piwil2

Gene Alias:
80kDa PIWIL2 short isoform; Cancer/testis antigen 80; CT80; HILI; Mili; Miwi like; Miwi likw; piwi like homolog 2; piwi like RNA-mediated gene silencing 2; Piwil1l; Piwil2; PIWI-L2; piwil2-like protein; piwi-like 2; piwi-like homolog 2; Piwi-like protein 2; piwi-like RNA-mediated gene silencing 2; testicular tissue protein Li 141

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57746

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3181

--


Antigen:
Mili / PiwiL2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8CDG1

Gene Symbols:
Piwil2

Immunogen:
This Mili / PiwiL2 antibody was raised against full-length recombinant mouse MILI / PIWIL2 protein.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Clone:
17.8

Conjugate:
Unconjugated

Gene:
Piwil2

Gene Alias:
80kDa PIWIL2 short isoform; Cancer/testis antigen 80; CT80; HILI; Mili; Miwi like; Miwi likw; piwi like homolog 2; piwi like RNA-mediated gene silencing 2; Piwil1l; Piwil2; PIWI-L2; piwil2-like protein; piwi-like 2; piwi-like homolog 2; Piwi-like protein 2; piwi-like RNA-mediated gene silencing 2; testicular tissue protein Li 141

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57746

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3184

--


Antigen:
Notch1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
P46531, Q07008

Gene Symbols:
Notch1

Immunogen:
This Notch1 antibody was raised against a recombinant protein corresponding to the intracellular domain of human Notch1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
ICN 5B5

Conjugate:
Unconjugated

Gene:
Notch1

Gene Alias:
9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25496, 4851

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid