50-199-3343

ASH2L Monoclonal Antibody (4C5), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3343-Each-of-1 In Stock ₹ 10,780.56

50-199-3343 - Each of 1

₹ 10,780.56

In Stock

Quantity

1

Base Price: ₹ 10,780.56

GST (18%): ₹ 1,940.501

Total Price: ₹ 12,721.061

Antigen

ASH2L

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q9UBL3

Gene Symbols

ASH2L

Immunogen

This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.

Quantity

10 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

4C5

Conjugate

Unconjugated

Gene

ASH2L

Gene Alias

ASH 2; ASH2; ash2 (absent, small, or homeotic)-like; ash2 (absent, small, or homeotic)-like (Drosophila); ASH2 LIKE; ASH2 like histone lysine methyltransferase complex subunit; ASH2 like protein; ASH2 like, histone lysine methyltransferase complex subunit; Ash2l; ASH2L1; ASH2L2; ash2-like; ASH2-like protein; BOS_23936; Bre 2; Bre2; LOC100338600; Set1/Ash2 histone methyltransferase complex subunit ASH2

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9070

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator
  • Its predicted molecular weight is 68.7kDa
  • Alternative splicing results in possible isoforms at 60 kDa & 56.5 kDa)
  • Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif
  • Homology to mouse ASH2L is 90%
  • ASH2L is predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes as well as leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami
  • Differentiation inducers (e.g
  • phorbol ester and hemin) cause different expression patterns in these cell lines, suggesting that ASH2L plays a role in hematopoiesis and is associated with particular types of leukemia
  • In addition ASH2L has been suggested to interact with beta-tubulin and beta-catenin.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-3343

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Antigen:
ASH2L

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q9UBL3

Gene Symbols:
ASH2L

Immunogen:
This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
4C5

Conjugate:
Unconjugated

Gene:
ASH2L

Gene Alias:
ASH 2; ASH2; ash2 (absent, small, or homeotic)-like; ash2 (absent, small, or homeotic)-like (Drosophila); ASH2 LIKE; ASH2 like histone lysine methyltransferase complex subunit; ASH2 like protein; ASH2 like, histone lysine methyltransferase complex subunit; Ash2l; ASH2L1; ASH2L2; ash2-like; ASH2-like protein; BOS_23936; Bre 2; Bre2; LOC100338600; Set1/Ash2 histone methyltransferase complex subunit ASH2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9070

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3346

--


Antigen:
Phospho-SIRT2 (Ser331)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8IXJ6

Gene Symbols:
SIRT2

Immunogen:
This antibody was raised against a synthetic peptide corresponding to human SIRT2 phosphorylated at Serine 331.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
6B5

Conjugate:
Unconjugated

Gene:
SIRT2

Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22933

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3347

--


Antigen:
Phospho-SIRT2 (Ser331)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8IXJ6

Gene Symbols:
SIRT2

Immunogen:
This antibody was raised against a synthetic peptide corresponding to human SIRT2 phosphorylated at Serine 331.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
6B5

Conjugate:
Unconjugated

Gene:
SIRT2

Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22933

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3350

--


Antigen:
SNAI1 / Snail

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
O95863

Gene Symbols:
Snai1

Immunogen:
This antibody was raised against a full-length recombinant protein corresponding to human SNAI1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry, Western Blot

Clone:
9H2

Conjugate:
Unconjugated

Gene:
Snai1

Gene Alias:
AI194338; dJ710H13.1; Protein sna; Protein snail homolog 1; SLUGH2; Sna; Sna protein; Sna1; SNAH; Snai1; SNAIL; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6615

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid