50-199-3204

WRN Monoclonal Antibody (195C), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3204-Each-of-1 In Stock ₹ 50,480.40

50-199-3204 - Each of 1

₹ 50,480.40

In Stock

Quantity

1

Base Price: ₹ 50,480.40

GST (18%): ₹ 9,086.472

Total Price: ₹ 59,566.872

Antigen

WRN

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q14191

Gene Symbols

WRN

Immunogen

This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone

195C

Conjugate

Unconjugated

Gene

WRN

Gene Alias

AI846146; DKFZp686C2056; DNA helicase, RecQ-like type 3; Exonuclease WRN; RecQ protein-like 2; RECQ3; RECQL2; RECQL3; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome ATP-dependent helicase homolog; Werner syndrome homolog (human); Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like; Wrn

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

7486

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Fischer Scientific

50-199-3205

--

Img

Fischer Scientific

50-199-3178

--

Img

Fischer Scientific

50-199-3179

--

Img

Fischer Scientific

50-199-3436

--

Img

Fischer Scientific

50-227-7256

--

Img

Fischer Scientific

50-199-3437

--

Img

Fischer Scientific

50-199-3019

--

Img

Fischer Scientific

50-199-3343

--

Description

  • This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases
  • DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair
  • This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization
  • It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease
  • Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks
  • Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-3204

--


Antigen:
WRN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q14191

Gene Symbols:
WRN

Immunogen:
This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
195C

Conjugate:
Unconjugated

Gene:
WRN

Gene Alias:
AI846146; DKFZp686C2056; DNA helicase, RecQ-like type 3; Exonuclease WRN; RecQ protein-like 2; RECQ3; RECQL2; RECQL3; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome ATP-dependent helicase homolog; Werner syndrome homolog (human); Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like; Wrn

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7486

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3205

--


Antigen:
WRN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q14191

Gene Symbols:
WRN

Immunogen:
This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
195C

Conjugate:
Unconjugated

Gene:
WRN

Gene Alias:
AI846146; DKFZp686C2056; DNA helicase, RecQ-like type 3; Exonuclease WRN; RecQ protein-like 2; RECQ3; RECQL2; RECQL3; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome ATP-dependent helicase homolog; Werner syndrome homolog (human); Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like; Wrn

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7486

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3206

--


Antigen:
LXR-alpha

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q13133, Q9Z0Y9

Gene Symbols:
NR1H3

Immunogen:
This LXR-alpha antibody was raised against a peptide in the N-terminal region of human LXR-alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; Liver X receptor alpha; LXR; LXR alpha; LXRA; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062, 22259

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3207

--


Antigen:
LXR-alpha

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q13133, Q9Z0Y9

Gene Symbols:
NR1H3

Immunogen:
This LXR-alpha antibody was raised against a peptide in the N-terminal region of human LXR-alpha.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; Liver X receptor alpha; LXR; LXR alpha; LXRA; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062, 22259

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid