50-199-3419

RYBP Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-3419-Each-of-1 In Stock ₹ 12,834.00

50-199-3419 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

RYBP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rybp

Gene Alias

2410018J24Rik; AAP1; APAP-1; Apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; RYBP; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23429, 56353

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

Lot-Specific

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q8CCI5, Q8N488

Gene Symbols

Rybp

Immunogen

This antibody was raised against a peptide within the C-terminal region of human RYBP.

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • RYBP involves component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development
  • PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility
  • Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females
  • May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites
  • Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes
  • May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis
  • May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1
  • May bind to DNA
  • May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-3419

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Antigen:
RYBP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rybp

Gene Alias:
2410018J24Rik; AAP1; APAP-1; Apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; RYBP; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23429, 56353

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8CCI5, Q8N488

Gene Symbols:
Rybp

Immunogen:
This antibody was raised against a peptide within the C-terminal region of human RYBP.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-3420

--


Antigen:
Mi-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
9530019N15Rik; AA617397; ATP-dependent helicase CHD4; BC005710; CHD4; CHD-4; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; D6Ertd380e; Mi-2; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; MI2B; Mi-2b; Mi-2beta; Mi2-beta; mKIAA4075

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This antibody was raised against a synthetic peptide corresponding to amino acid residues 1641-1662 of Drosophila Mi-2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Drosophila

Product Type:
Antibody

Isotype:
IgG2c

Img

Fischer Scientific

50-199-3421

--


Antigen:
Mi-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
9530019N15Rik; AA617397; ATP-dependent helicase CHD4; BC005710; CHD4; CHD-4; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; D6Ertd380e; Mi-2; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; MI2B; Mi-2b; Mi-2beta; Mi2-beta; mKIAA4075

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This antibody was raised against a synthetic peptide corresponding to amino acid residues 1641-1662 of Drosophila Mi-2.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Drosophila

Product Type:
Antibody

Isotype:
IgG2c

Img

Fischer Scientific

50-199-3426

--


Antigen:
CHD3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CHD3

Gene Alias:
2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CHD3; CHD-3; Chd7; chromodomain helicase DNA binding protein 3; Chromodomain-helicase-DNA-binding protein 3; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; Mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
40111

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
O16102

Gene Symbols:
CHD3

Immunogen:
This antibody was raised against a synthetic peptide corresponding to amino acid residues 865-885 of Drosophila CHD3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Drosophila

Product Type:
Antibody

Isotype:
IgG1