50-199-3535
CABIN1 Polyclonal Antibody, Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-3535-Each-of-1 | In Stock | ₹ 12,834.00 |
50-199-3535 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,834.00
GST (18%): ₹ 2,310.12
Total Price: ₹ 15,144.12
Antigen
CABIN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CABIN1
Gene Alias
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23523
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
Lot-Specific
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.
Q9Y6J0
Gene Symbols
CABIN1
Immunogen
This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Calcineurin binding protein (Cabin-1) and the corresponding rat homolog, designated Cain, are widely expressed nuclear phosphoproteins that regulate the serine/threonine phosphotase activity of calcineurin and influence T cell signaling and apoptosis
- Calcineurin is required for the transcriptional activation of cytokines and the activation of various transcription factors, including NFAT, NFκB and AP-1, involved in T cell receptor (TCR)-mediated signaling
- The regulation of calcineurin depends on the changes in intracellular calcium concentrations and the activity of protein kinase C
- TCR activation results in PKC inducing the hyperphosphorylation of Cabin-1, which facilitates the high affinity binding of Cabin-1 to calcineurin
- This complex formation, in turn, inhibits calcineurin activity and attenuates TCR-mediated signaling
- Cabin-1 also associates directly with MEF-2 proteins, a family of transcription factors that regulate apoptosis signaling in T cells
- This association between Cabin-1 and MEF-2 leads to the inhibition of MEF-2-mediated gene transcription and the inhibition of apoptosis.
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Antigen: CABIN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CABIN1
Gene Alias: A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23523
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: Q9Y6J0
Gene Symbols: CABIN1
Immunogen: This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CABIN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABIN1
Gene Alias:
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23523
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
Q9Y6J0
Gene Symbols:
CABIN1
Immunogen:
This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TNF
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Tnf
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7124
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P01375
Gene Symbols: Tnf
Immunogen: This antibody was raised against Human TNF.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TNF
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Tnf
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7124
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P01375
Gene Symbols:
Tnf
Immunogen:
This antibody was raised against Human TNF.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: TNF
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Tnf
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7124
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P01375
Gene Symbols: Tnf
Immunogen: This antibody was raised against Human TNF.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TNF
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Tnf
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7124
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P01375
Gene Symbols:
Tnf
Immunogen:
This antibody was raised against Human TNF.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: IFNA1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IFNA2
Gene Alias: alpha-2a interferon; Gm12597; Ifa1; Ifa2; IFL; IFN; IFN alpha; IFN a; IFN1@; IFNA; IFNA@; Ifna1; IFNA13; Ifna15; IFNA2; IFNA2A; IFNA2B; IFNA2C; IFNA3; IFNA6; Ifnaa; IFNAalphaIFN-alpha-1/13; IFNalpha; IFN-ALPHA; IFN-alpha 1b; IFN-alpha1; IFN-alpha-1; IFN-alpha-1/13; IFN-alpha-2; IFN-alpha-6; IFN-alphaA; IFN-alphaD; IFN-gamma; IFNa; INFA2; interferon; interferon alpha; interferon alpha 1; interferon alpha 15; interferon alpha 1b; interferon alpha 2; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha-1; Interferon alpha-1/13; Interferon alpha-2; Interferon alpha-A; Interferon alpha-D; Interferon type A1/A2; interferon type A3; interferon, alpha 1; interferon, alpha 2; interferon-alpha; interferon-alpha 1; interferon-alpha1; interferon-alpha-6; LeIF A; LeIF D; MGC138207; MGC138505; MGC138507; MuIFN-alpha-A; novel interferon alpha (Ifna) family member; OTTMUSG00000007655
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3439, 3440
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P01562, P01563
Gene Symbols: IFNA1, IFNA2
Immunogen: This antibody was raised against Human IFNA1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
IFNA1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IFNA2
Gene Alias:
alpha-2a interferon; Gm12597; Ifa1; Ifa2; IFL; IFN; IFN alpha; IFN a; IFN1@; IFNA; IFNA@; Ifna1; IFNA13; Ifna15; IFNA2; IFNA2A; IFNA2B; IFNA2C; IFNA3; IFNA6; Ifnaa; IFNAalphaIFN-alpha-1/13; IFNalpha; IFN-ALPHA; IFN-alpha 1b; IFN-alpha1; IFN-alpha-1; IFN-alpha-1/13; IFN-alpha-2; IFN-alpha-6; IFN-alphaA; IFN-alphaD; IFN-gamma; IFNa; INFA2; interferon; interferon alpha; interferon alpha 1; interferon alpha 15; interferon alpha 1b; interferon alpha 2; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha-1; Interferon alpha-1/13; Interferon alpha-2; Interferon alpha-A; Interferon alpha-D; Interferon type A1/A2; interferon type A3; interferon, alpha 1; interferon, alpha 2; interferon-alpha; interferon-alpha 1; interferon-alpha1; interferon-alpha-6; LeIF A; LeIF D; MGC138207; MGC138505; MGC138507; MuIFN-alpha-A; novel interferon alpha (Ifna) family member; OTTMUSG00000007655
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3439, 3440
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P01562, P01563
Gene Symbols:
IFNA1, IFNA2
Immunogen:
This antibody was raised against Human IFNA1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a