50-199-3534
CABIN1 Polyclonal Antibody, Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-3534-Each-of-1 | In Stock | ₹ 50,480.40 |
50-199-3534 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
CABIN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CABIN1
Gene Alias
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23523
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
Lot-Specific
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.
Q9Y6J0
Gene Symbols
CABIN1
Immunogen
This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Calcineurin binding protein (Cabin-1) and the corresponding rat homolog, designated Cain, are widely expressed nuclear phosphoproteins that regulate the serine/threonine phosphotase activity of calcineurin and influence T cell signaling and apoptosis
- Calcineurin is required for the transcriptional activation of cytokines and the activation of various transcription factors, including NFAT, NFκB and AP-1, involved in T cell receptor (TCR)-mediated signaling
- The regulation of calcineurin depends on the changes in intracellular calcium concentrations and the activity of protein kinase C
- TCR activation results in PKC inducing the hyperphosphorylation of Cabin-1, which facilitates the high affinity binding of Cabin-1 to calcineurin
- This complex formation, in turn, inhibits calcineurin activity and attenuates TCR-mediated signaling
- Cabin-1 also associates directly with MEF-2 proteins, a family of transcription factors that regulate apoptosis signaling in T cells
- This association between Cabin-1 and MEF-2 leads to the inhibition of MEF-2-mediated gene transcription and the inhibition of apoptosis.
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Antigen: CABIN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CABIN1
Gene Alias: A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23523
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: Q9Y6J0
Gene Symbols: CABIN1
Immunogen: This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CABIN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABIN1
Gene Alias:
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23523
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
Q9Y6J0
Gene Symbols:
CABIN1
Immunogen:
This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CABIN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CABIN1
Gene Alias: A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23523
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: Q9Y6J0
Gene Symbols: CABIN1
Immunogen: This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CABIN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABIN1
Gene Alias:
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23523
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
Q9Y6J0
Gene Symbols:
CABIN1
Immunogen:
This antibody was raised against a peptide within the C-terminal region of human CABIN1.
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TNF
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Tnf
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7124
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P01375
Gene Symbols: Tnf
Immunogen: This antibody was raised against Human TNF.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TNF
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Tnf
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7124
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P01375
Gene Symbols:
Tnf
Immunogen:
This antibody was raised against Human TNF.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: TNF
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Tnf
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7124
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P01375
Gene Symbols: Tnf
Immunogen: This antibody was raised against Human TNF.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TNF
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Tnf
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7124
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P01375
Gene Symbols:
Tnf
Immunogen:
This antibody was raised against Human TNF.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a