50-199-3565
Nanog Monoclonal Antibody (2E6E1), Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-3565-Each-of-1 | In Stock | ₹ 10,780.56 |
50-199-3565 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 10,780.56
GST (18%): ₹ 1,940.501
Total Price: ₹ 12,721.061
Antigen
Nanog
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.
Q80Z64
Gene Symbols
NANOG
Immunogen
This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Quantity
10 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Clone
2E6E1
Conjugate
Unconjugated
Gene
NANOG
Gene Alias
2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
71950
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
- NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
- Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
- Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
- Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
- Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
- Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
- The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
- Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
- Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
- When overexpressed, NANOG promotes cells to enter into S phase and proliferation
- Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.
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Antigen: Nanog
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: Q80Z64
Gene Symbols: NANOG
Immunogen: This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: 2E6E1
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 71950
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Nanog
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
Q80Z64
Gene Symbols:
NANOG
Immunogen:
This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
2E6E1
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
71950
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H3ac (pan-acetyl)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: __
Gene Symbols: __
Immunogen: This antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of human Histone H3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H3ac (pan-acetyl)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
This antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of human Histone H3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H3ac (pan-acetyl)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: __
Gene Symbols: __
Immunogen: This antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of human Histone H3.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H3ac (pan-acetyl)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
This antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of human Histone H3.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PARP-1 N-terminal
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P09874
Gene Symbols: Parp1
Immunogen: This antibody was raised against a His-Tagged fusion protein corresponding to the N-terminal half of human PARP-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP sequencing (ChIP-seq), Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: Parp1
Gene Alias: 5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein p
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 142
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PARP-1 N-terminal
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P09874
Gene Symbols:
Parp1
Immunogen:
This antibody was raised against a His-Tagged fusion protein corresponding to the N-terminal half of human PARP-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP sequencing (ChIP-seq), Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
Parp1
Gene Alias:
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein p
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
142
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid