50-199-3975

Aurora B Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3975-Each-of-1 In Stock ₹ 50,480.40

50-199-3975 - Each of 1

₹ 50,480.40

In Stock

Quantity

1

Base Price: ₹ 50,480.40

GST (18%): ₹ 9,086.472

Total Price: ₹ 59,566.872

Antigen

Aurora B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AURKB

Gene Alias

AIE2; AIK1; Aik2; AIK3; AIM1; AIM-1; AIRK2; AIRK3; AL022959; Ark2; ARK-2; ARK3; ARK-3; AurB; Aurkb; aurkb-sv1; aurkb-sv2; AURKC; Aurora 1; Aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; Aurora kinase B; aurora kinase B; serine/threonine-protein kinase 12; aurora kinase B-Sv1; aurora kinase B-Sv2; Aurora kinase C; Aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; BOS_18918; EC 2.7.11.1; IPL1; NP_004208; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; STK1; STK-1; STK12; STK13; STK5

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.

O70126, Q96GD4

Gene Symbols

AURKB

Immunogen

This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.

Regulatory Status

RUO

Gene ID (Entrez)

20877, 9212

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Aurora-B kinase (AurB) is a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC)
  • This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
  • CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
  • Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
  • Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
  • AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
  • Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-3975

--


Antigen:
Aurora B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
AIE2; AIK1; Aik2; AIK3; AIM1; AIM-1; AIRK2; AIRK3; AL022959; Ark2; ARK-2; ARK3; ARK-3; AurB; Aurkb; aurkb-sv1; aurkb-sv2; AURKC; Aurora 1; Aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; Aurora kinase B; aurora kinase B; serine/threonine-protein kinase 12; aurora kinase B-Sv1; aurora kinase B-Sv2; Aurora kinase C; Aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; BOS_18918; EC 2.7.11.1; IPL1; NP_004208; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; STK1; STK-1; STK12; STK13; STK5

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
O70126, Q96GD4

Gene Symbols:
AURKB

Immunogen:
This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.

Regulatory Status:
RUO

Gene ID (Entrez):
20877, 9212

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3976

--


Antigen:
Aurora B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
AIE2; AIK1; Aik2; AIK3; AIM1; AIM-1; AIRK2; AIRK3; AL022959; Ark2; ARK-2; ARK3; ARK-3; AurB; Aurkb; aurkb-sv1; aurkb-sv2; AURKC; Aurora 1; Aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; Aurora kinase B; aurora kinase B; serine/threonine-protein kinase 12; aurora kinase B-Sv1; aurora kinase B-Sv2; Aurora kinase C; Aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; BOS_18918; EC 2.7.11.1; IPL1; NP_004208; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; STK1; STK-1; STK12; STK13; STK5

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
O70126, Q96GD4

Gene Symbols:
AURKB

Immunogen:
This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.

Regulatory Status:
RUO

Gene ID (Entrez):
20877, 9212

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3977

--


Antigen:
LAP2 alpha

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TMPO

Gene Alias:
5630400D24Rik; AI195756; AI606875; AW214352; AW547477; CMD1T; lamina-associated polypeptide 2; Lamina-associated polypeptide 2, isoform alpha; Lamina-associated polypeptide 2, isoform beta; Lamina-associated polypeptide 2, isoforms alpha/zeta; Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma; Lamina-associated polypeptide 2, isoforms beta/gamma; Lap2; LEM domain containing 4; LEMD4; PRO0868; Splenin; Thymopentin; Thymopoietin; Thymopoietin (lamina associated polypeptide 2); thymopoietin beta; Thymopoietin isoform alpha; Thymopoietin isoform beta; Thymopoietin isoforms alpha/zeta; Thymopoietin isoforms beta/delta/epsilon/gamma; Thymopoietin, isoforms beta/gamma; Thymopoietin-related peptide isoform alpha; Thymopoietin-related peptide isoforms beta/gamma; Tmpo; TP; TP alpha; TP alpha/zeta; TP beta; TP beta/delta/epsilon/gamma; TP beta/gamma; TP5; TPRP isoform alpha; TPRP isoforms beta/gamma

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
ascites with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
P42166

Gene Symbols:
TMPO

Immunogen:
This LAP2 alpha antibody was raised against a peptide including the C-terminus of human LAP2 alpha.

Regulatory Status:
RUO

Gene ID (Entrez):
7112

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3978

--


Antigen:
LAP2 alpha

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TMPO

Gene Alias:
5630400D24Rik; AI195756; AI606875; AW214352; AW547477; CMD1T; lamina-associated polypeptide 2; Lamina-associated polypeptide 2, isoform alpha; Lamina-associated polypeptide 2, isoform beta; Lamina-associated polypeptide 2, isoforms alpha/zeta; Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma; Lamina-associated polypeptide 2, isoforms beta/gamma; Lap2; LEM domain containing 4; LEMD4; PRO0868; Splenin; Thymopentin; Thymopoietin; Thymopoietin (lamina associated polypeptide 2); thymopoietin beta; Thymopoietin isoform alpha; Thymopoietin isoform beta; Thymopoietin isoforms alpha/zeta; Thymopoietin isoforms beta/delta/epsilon/gamma; Thymopoietin, isoforms beta/gamma; Thymopoietin-related peptide isoform alpha; Thymopoietin-related peptide isoforms beta/gamma; Tmpo; TP; TP alpha; TP alpha/zeta; TP beta; TP beta/delta/epsilon/gamma; TP beta/gamma; TP5; TPRP isoform alpha; TPRP isoforms beta/gamma

Host Species:
Mouse

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
ascites with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
P42166

Gene Symbols:
TMPO

Immunogen:
This LAP2 alpha antibody was raised against a peptide including the C-terminus of human LAP2 alpha.

Regulatory Status:
RUO

Gene ID (Entrez):
7112

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid