50-199-4010
IRF-3 Polyclonal Antibody, Active Motif™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-4010-Each-of-1 | In Stock | ₹ 51,490.01 |
50-199-4010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,490.01
GST (18%): ₹ 9,268.202
Total Price: ₹ 60,758.212
Antigen
IRF-3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species
Rabbit
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.
Q14653
Gene Symbols
IRF3
Immunogen
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Regulatory Status
RUO
Gene ID (Entrez)
3661
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
Compare Similar Items
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Antigen: IRF-3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Regulatory Status: RUO
Gene ID (Entrez): 3661
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IRF-3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Regulatory Status:
RUO
Gene ID (Entrez):
3661
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IRF-3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Regulatory Status: RUO
Gene ID (Entrez): 3661
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IRF-3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Regulatory Status:
RUO
Gene ID (Entrez):
3661
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H4K31me1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Rabbit
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Dot Blot, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.: __
Gene Symbols: __
Immunogen: This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H4K31me1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Rabbit
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Dot Blot, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H3K23me1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H3C15
Gene Alias: __
Host Species: Rabbit
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Dot Blot, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.: Q71DI3
Gene Symbols: H3C15, H3C2
Immunogen: This Histone H3 monomethyl Lys23 antibody was raised against a peptide containing monomethyl Lys23 of human histone H3.
Regulatory Status: RUO
Gene ID (Entrez): 126961, 333932, 8358
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H3K23me1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H3C15
Gene Alias:
__
Host Species:
Rabbit
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Dot Blot, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Accession No.:
Q71DI3
Gene Symbols:
H3C15, H3C2
Immunogen:
This Histone H3 monomethyl Lys23 antibody was raised against a peptide containing monomethyl Lys23 of human histone H3.
Regulatory Status:
RUO
Gene ID (Entrez):
126961, 333932, 8358
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid