50-199-4011

IRF-3 Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-4011-Each-of-1 In Stock ₹ 12,834.00

50-199-4011 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

IRF-3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species

Rabbit

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.

Q14653

Gene Symbols

IRF3

Immunogen

This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.

Regulatory Status

RUO

Gene ID (Entrez)

3661

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-4011

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Antigen:
IRF-3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
Q14653

Gene Symbols:
IRF3

Immunogen:
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.

Regulatory Status:
RUO

Gene ID (Entrez):
3661

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4012

--


Antigen:
Histone H4K31me1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4013

--


Antigen:
Histone H3K23me1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H3C15

Gene Alias:
__

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
Q71DI3

Gene Symbols:
H3C15, H3C2

Immunogen:
This Histone H3 monomethyl Lys23 antibody was raised against a peptide containing monomethyl Lys23 of human histone H3.

Regulatory Status:
RUO

Gene ID (Entrez):
126961, 333932, 8358

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-4014

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Antigen:
Histone H3K9me2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Di histone H3/c; dimethyl H3; di-methyl H3; Dimethyl Histone H3; di-methyl histone H3; Di-Methyl-H3 K9; Di-Methyl-H3 Lys9; Di-Methyl-Histone H3 K9; Di-Methyl-Histone H3 Lys9; Dmel\CG31613; Dmel_CG31613; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K9me2; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3b; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Immunogen:
This Histone H3 dimethyl Lys9 antibody was raised against a peptide including dimethyl-lysine 9 of histone H3.

Regulatory Status:
RUO

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid