50-255-0788
EZH2 Monoclonal Antibody (AC22), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-255-0788-Each-of-1 | In Stock | ₹ 38,502.00 |
50-255-0788 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,502.00
GST (18%): ₹ 6,930.36
Total Price: ₹ 45,432.36
Antigen
EZH2
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
Q15910, Q61188
Gene Symbols
EZH2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14056, 2146, 312299
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Isotype
IgG2a κ
Applications
Immunocytochemistry, Immunohistochemistry
Clone
AC22
Conjugate
eFluor 660
Gene
EZH2
Gene Alias
an, enhancer of zeste 2 polycomb repressive complex 2 subunit, enhancer of zeste homolog 2, enhancer of zeste homolog 2 (Drosophila), ENX 1, ENX1, Enx-1, Enx1h, EZH 2, EZH1, EZH2, EZH-2, EZH2b, histone-lysine N-methyltransferase EZH2, KMT6, KMT6A, lysine N-methyltransferase 6, mKIAA4065, OTTHUMP00000213774, OTTHUMP00000213778, OTTHUMP00000213779, OTTHUMP00000213780, WVS, WVS2
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Related Products
Description
- The monoclonal antibody AC22 recognizes EZH2 (Enhancer of zeste homolog 2), a member of the polycomb group (PcG) proteins responsible for repression of gene expression through recognition and modification of histone methylation and chromatin structure
- EZH2 comprises the catalytic subunit of the polycomb repressive complex 2 (PRC2) and directly represses gene expression through methylation of histone H3 on lysine 27 (H3K27) as well as direct protein targets such as GATA4
- The PRC2 complex gene repression is necessary for proper development and differentiation
- Underexpression of EZH2 is linked to abnormal developmental patterning and a loss of stem cell pluripotency, while overexpression of EZH2 is present in many tumors and correlates with poor prognosis in melanoma, breast, and prostate cancer
- Applications Reported: This AC22 antibody has been reported for use in microscopy, and immunocytochemistry
- Applications Tested: This AC22 antibody has been tested by immunocytochemistry of methanol-fixed cells and can be used at less than or equal to 20 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family
- PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations
- This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein
- EZH2 may play a role in the hematopoietic and central nervous systems
- Mutations affecting EZH2 can cause Weaver syndrome (WVS).
Compare Similar Items
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Antigen: EZH2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q15910, Q61188
Gene Symbols: EZH2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14056, 2146, 312299
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry
Clone: AC22
Conjugate: eFluor 660
Gene: EZH2
Gene Alias: an, enhancer of zeste 2 polycomb repressive complex 2 subunit, enhancer of zeste homolog 2, enhancer of zeste homolog 2 (Drosophila), ENX 1, ENX1, Enx-1, Enx1h, EZH 2, EZH1, EZH2, EZH-2, EZH2b, histone-lysine N-methyltransferase EZH2, KMT6, KMT6A, lysine N-methyltransferase 6, mKIAA4065, OTTHUMP00000213774, OTTHUMP00000213778, OTTHUMP00000213779, OTTHUMP00000213780, WVS, WVS2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
EZH2
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q15910, Q61188
Gene Symbols:
EZH2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14056, 2146, 312299
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry
Clone:
AC22
Conjugate:
eFluor 660
Gene:
EZH2
Gene Alias:
an, enhancer of zeste 2 polycomb repressive complex 2 subunit, enhancer of zeste homolog 2, enhancer of zeste homolog 2 (Drosophila), ENX 1, ENX1, Enx-1, Enx1h, EZH 2, EZH1, EZH2, EZH-2, EZH2b, histone-lysine N-methyltransferase EZH2, KMT6, KMT6A, lysine N-methyltransferase 6, mKIAA4065, OTTHUMP00000213774, OTTHUMP00000213778, OTTHUMP00000213779, OTTHUMP00000213780, WVS, WVS2
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: CD207 (Langerin)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q8VBX4
Gene Symbols: CD207
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 246278
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: eBioRMUL.2
Conjugate: eFluor 660
Gene: CD207
Gene Alias: CD 207 antigen, CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, CD207 molecule, langerin, CLEC4K, C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, Langerhans cell specific c-type lectin, langerin, RGD1565913
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Antigen:
CD207 (Langerin)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q8VBX4
Gene Symbols:
CD207
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
246278
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
eBioRMUL.2
Conjugate:
eFluor 660
Gene:
CD207
Gene Alias:
CD 207 antigen, CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, CD207 molecule, langerin, CLEC4K, C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, Langerhans cell specific c-type lectin, langerin, RGD1565913
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Antigen: CD20
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P11836
Gene Symbols: Ms4a1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 102118491, 696843, 931
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: L26
Conjugate: eFluor 660
Gene: Ms4a1
Gene Alias: AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7
Host Species: Mouse
Quantity: 25μg
Primary or Secondary: Primary
Target Species: Cynomolgus Monkey, Human, Rhesus Monkey
Form: Liquid
Antigen:
CD20
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P11836
Gene Symbols:
Ms4a1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
102118491, 696843, 931
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
L26
Conjugate:
eFluor 660
Gene:
Ms4a1
Gene Alias:
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7
Host Species:
Mouse
Quantity:
25μg
Primary or Secondary:
Primary
Target Species:
Cynomolgus Monkey, Human, Rhesus Monkey
Form:
Liquid
Antigen: BAZ2A
Classification: Polyclonal
Concentration: Conc. Not Determined
Formulation: whole serum with <0.1% sodium azide
Gene Accession No.: Q91YE5, Q9UIF9
Gene Symbols: BAZ2A
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 11176, 116848
Content And Storage: -20°, C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: ChIP Assay, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: BAZ2A
Gene Alias: AA415431, BAZ2A, bromodomain adjacent to zinc finger domain 2A, bromodomain adjacent to zinc finger domain protein 2A, bromodomain adjacent to zinc finger domain, 2A, C030005G16Rik, C78388, hWALp3, KIAA0314, mKIAA0314, TIP5, Transcription termination factor I-interacting protein 5, TTF-I interacting peptide 5, TTF-I-interacting protein 5, Walp3
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
BAZ2A
Classification:
Polyclonal
Concentration:
Conc. Not Determined
Formulation:
whole serum with <0.1% sodium azide
Gene Accession No.:
Q91YE5, Q9UIF9
Gene Symbols:
BAZ2A
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
11176, 116848
Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
ChIP Assay, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
BAZ2A
Gene Alias:
AA415431, BAZ2A, bromodomain adjacent to zinc finger domain 2A, bromodomain adjacent to zinc finger domain protein 2A, bromodomain adjacent to zinc finger domain, 2A, C030005G16Rik, C78388, hWALp3, KIAA0314, mKIAA0314, TIP5, Transcription termination factor I-interacting protein 5, TTF-I interacting peptide 5, TTF-I-interacting protein 5, Walp3
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid