50-245-841
PCNA Monoclonal Antibody (PC10 (3F81)), eFluor™ 615, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-245-841-Each-of-1 | In Stock | ₹ 38,502.00 |
50-245-841 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,502.00
GST (18%): ₹ 6,930.36
Total Price: ₹ 45,432.36
Antigen
PCNA
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P04961, P12004, P17918
Gene Symbols
Pcna
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18538, 25737, 5111
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Clone
PC10 (3F81)
Conjugate
eFluor 615
Gene
Pcna
Gene Alias
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The PC10 antibody recognizes the proliferating cell nuclear antigen (PCNA), a 36 kDa protein, also known as polymerase delta auxiliary protein
- PC10 antibody reacts with human, mouse, and rat PCNA
- The peak expression of PCNA occurs during the S-phase
- Applications Reported: This PC10 (a.k.a
- 3F81) antibody has been reported for use in immunohistochemical and immunocytochemical staining
- Applications Tested: This PC10 (a.k.a
- 3F81) antibody has been tested by immunocytochemistry of methanol-fixed MDCK cells and can be used at less than or equal to 0.5 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- This product has not been validated for flow cytometric analysis
- Filter Recommendation: When using this eFluor® 615 antibody conjugate, we recommend a filter that will capture the 615 emission wavelength (for example, Excitation 560/55, 585LP, Emission 645/75)
- A standard Alexa Fluor® 594 filter is acceptable
- Excitation: 595 nm; Emission: 615 nm
- Filtration: 0.2 μm post-manufacturing filtered
- PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways
- PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT)
- PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e
- relevant to prognosis)
- PCNA is a marker for cells in early G1 phase and S phase of the cell cycle
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication
- In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway
- Two transcript variants encoding the same protein have been found for PCNA
- Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
Compare Similar Items
Show Difference
Antigen: PCNA
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P04961, P12004, P17918
Gene Symbols: Pcna
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18538, 25737, 5111
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Clone: PC10 (3F81)
Conjugate: eFluor 615
Gene: Pcna
Gene Alias: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
PCNA
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P04961, P12004, P17918
Gene Symbols:
Pcna
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18538, 25737, 5111
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Clone:
PC10 (3F81)
Conjugate:
eFluor 615
Gene:
Pcna
Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a κ
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