53-981-082
Blood Group Antigen H (O) Type 1 Monoclonal Antibody (17-206), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-981-082-Each-of-1 | In Stock | ₹ 41,068.80 |
53-981-082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,068.80
GST (18%): ₹ 7,392.384
Total Price: ₹ 48,461.184
Antigen
Blood Group Antigen H (O) Type 1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
17-206
Conjugate
Alexa Fluor 488
Gene Alias
ABH; BG-H; BG-H1; group h
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Human
Product Type
Antibody
Isotype
IgG3
Related Products
Description
- The MAb 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells
- The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells
- The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases
- Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen)
- Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined
- The 17-206 antibody does not recognize blood group antigen H (O) type 2
- The H antigen is a precursor to the ABO blood group antigens, present in people of all common blood types
- The Bombay phenotype (hh) does not express antigen H on red blood cells, and therefore this type will also lack A or B antigens, similar to the O blood group
- However, unlike O group, the H antigen is absent, hence the individuals produce isoantibodies to antigen H as well as to both A and B antigens
- If they receive blood from someone with O blood group, the anti-H antibodies will bind to the H antigen on the red blood cells of the donor blood and destroy the RBCs by complement-mediated lysis
- Therefore, people with Bombay phenotype can receive blood only from other hh donors, although they can donate as though they were type O
- Some individuals with the blood group A1 may also be able to produce anti-H antibodies due to the complete conversion of all the H antigen to A1 antigen
- Production of the H antigen, or its deficiency in the Bombay phenotype, is controlled at the H locus on chromosome 19
- The H locus contains three exons that span more than 5 kb of genomic DNA, and encodes the fucosyltransferase that produces the H antigen on RBCs
- The H antigen is a carbohydrate sequence with carbohydrates linked mainly to protein (with a minor fraction attached to ceramide moiety).
Compare Similar Items
Show Difference
Antigen: Blood Group Antigen H (O) Type 1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 17-206
Conjugate: Alexa Fluor 488
Gene Alias: ABH; BG-H; BG-H1; group h
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG3
Antigen:
Blood Group Antigen H (O) Type 1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
17-206
Conjugate:
Alexa Fluor 488
Gene Alias:
ABH; BG-H; BG-H1; group h
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3
Antigen: Cytokeratin 18
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Clone: LDK18
Conjugate: Alexa Fluor 488
Gene Alias: cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Cytokeratin 18
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Clone:
LDK18
Conjugate:
Alexa Fluor 488
Gene Alias:
cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Blimp-1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 5E7
Conjugate: Alexa Fluor 488
Gene Alias: B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Blimp-1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
5E7
Conjugate:
Alexa Fluor 488
Gene Alias:
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Blimp-1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 5E7
Conjugate: Alexa Fluor 488
Gene Alias: B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Blimp-1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
5E7
Conjugate:
Alexa Fluor 488
Gene Alias:
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ