50-255-0871

CD4 Monoclonal Antibody (GK1.5), Brilliant Ultra Violet™ 737, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-255-0871-Each-of-1 In Stock ₹ 17,197.56

50-255-0871 - Each of 1

₹ 17,197.56

In Stock

Quantity

1

Base Price: ₹ 17,197.56

GST (18%): ₹ 3,095.561

Total Price: ₹ 20,293.121

Antigen

CD4

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P06332

Gene Symbols

CD4

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12504

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

GK1.5

Conjugate

Brilliant Ultraviolet 737

Gene

CD4

Gene Alias

Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

Description

  • The GK1.5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells
  • CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells
  • In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail
  • Binding of GK1.5 is blocked by RM4-5
  • Applications Reported: This GK1.5 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This GK1.5 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Brilliant Ultraviolet 737 is a tandem dye that emits at 732 nm and is intended for use on cytometers equipped with an ultraviolet (355 nm) laser
  • The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV
  • CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells
  • At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues
  • CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck
  • It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system
  • Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

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Fischer Scientific

50-255-0871

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P06332

Gene Symbols:
CD4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12504

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
GK1.5

Conjugate:
Brilliant Ultraviolet 737

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

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Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative, pH 7.2

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
4°, C

Form:
Liquid

Applications:
Functional Assay, Immunostaining, Neutralization

Clone:
eBio64CAP17

Conjugate:
Functional Grade

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Mouse

Quantity:
5 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
Lamin A

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P02545, P48678

Gene Symbols:
LMNA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16905, 4000

Content And Storage:
4°, C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
4A4-A4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A, lamin A/C, lamin A/C-like 1, lamin C, lamin C2, lamin-A/C, LDP1, LFP, LGMD1B, LMN1, Lmna, LMNA protein, LMNC, LMNL1, OTTHUMP00000015843, OTTHUMP00000015846, OTTHUMP00000015847, Prelamin-A/C, PRO1, renal carcinoma antigen NY-REN-32, unnamed protein product

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
__

Isotype:
IgG1 κ

Img

Bioworld

50-255-088

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