50-255-0884
MASH1 Monoclonal Antibody (24B72D11), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-255-0884-Each-of-1 | In Stock | ₹ 13,604.04 |
50-255-0884 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,604.04
GST (18%): ₹ 2,448.727
Total Price: ₹ 16,052.767
Antigen
MASH1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P19359, Q02067
Gene Symbols
Ascl1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17172, 64186
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
24B72D11
Conjugate
Unconjugated
Gene
Ascl1
Gene Alias
achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species
Mouse
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Description
- Description: The monoclonal antibody 24B72D11 recognizes mouse and rat Mammalian achaete-scute homolog 1 (MASH1), a 34 kDa basic helix-loop-helix (bHLH) transcription factor
- MASH1, like family members Olig2 and Ngn2, is expressed in progenitor cells throughout the nervous system and retina and is a key regulator of cell fate specification
- Expression of MASH1 is regulated by the Delta/Notch1 pathway through direct binding of Hes1 to MASH1 as well as competitive binding to MASH1 hetero-dimerizing proteins
- At a transcriptional level, MASH1 expression is controlled by notch-mediated regulation of sox2, which binds to the MASH1 promoter region up-regulating expression
- MASH1 has been implicated in the formation of multiple neural cell types including dopaminergic, serotonergic, glutaminergic and GABAergic neurons
- Overexpression of MASH1 has been shown in small cell lung carcinoma and medullary thyroid cancer
- Applications Reported: This 24B72D11 antibody has been reported for use in western blotting, immunohistochemical staining of frozen tissue sections, and immunocytochemistry
- Applications Tested: This 24B72D11 antibody has been tested by western blot on reduced PC12 cells and can be used at less than or equal to 5 μg/mL
- The 24B72D11 antibody has also been tested by immunocytochemistry on fixed and permeablized PC12 cells at can be used at less than or equal to 20 μg/mL
- ASCL1 (also known as ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system
- Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons
- ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system
- The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features
- Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.
Compare Similar Items
Show Difference
Antigen: MASH1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P19359, Q02067
Gene Symbols: Ascl1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17172, 64186
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: 24B72D11
Conjugate: Unconjugated
Gene: Ascl1
Gene Alias: achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
MASH1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P19359, Q02067
Gene Symbols:
Ascl1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17172, 64186
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
24B72D11
Conjugate:
Unconjugated
Gene:
Ascl1
Gene Alias:
achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD56 (NCAM)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P13591
Gene Symbols: Ncam1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4684
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 5tukon56
Conjugate: Unconjugated
Gene: Ncam1
Gene Alias: adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD56 (NCAM)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P13591
Gene Symbols:
Ncam1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4684
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
5tukon56
Conjugate:
Unconjugated
Gene:
Ncam1
Gene Alias:
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD47
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q08722
Gene Symbols: CD47
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 961
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: 2D3
Conjugate: Unconjugated
Gene: CD47
Gene Alias: 9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species: Mouse
Quantity: 10 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD47
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q08722
Gene Symbols:
CD47
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
961
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
2D3
Conjugate:
Unconjugated
Gene:
CD47
Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species:
Mouse
Quantity:
10 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: ErbB4 (Her4)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q15303, Q61527
Gene Symbols: ERBB4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13869, 2066
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: HFR1
Conjugate: Biotin
Gene: ERBB4
Gene Alias: 4ICD, ALS19, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, avian erythroblastosis oncogene B 4, c-erbB-4, erb-b2 receptor tyrosine kinase 4, Erbb4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, Her4, human epidermal growth factor receptor 4, Mer4, OTTHUMP00000209432, p180erbB4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-4, s80HER4, Tyro-2, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), v-erb-b2 avian erythroblastic leukemia viral oncogene 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: __
Isotype: IgG2b κ
Antigen:
ErbB4 (Her4)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q15303, Q61527
Gene Symbols:
ERBB4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13869, 2066
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
HFR1
Conjugate:
Biotin
Gene:
ERBB4
Gene Alias:
4ICD, ALS19, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, avian erythroblastosis oncogene B 4, c-erbB-4, erb-b2 receptor tyrosine kinase 4, Erbb4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, Her4, human epidermal growth factor receptor 4, Mer4, OTTHUMP00000209432, p180erbB4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-4, s80HER4, Tyro-2, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), v-erb-b2 avian erythroblastic leukemia viral oncogene 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
__
Isotype:
IgG2b κ