50-271-8464

TNF alpha Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-271-8464-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8464 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

TNF alpha

Classification

Polyclonal

Conjugate

Biotin

Gene

Tnf

Gene Alias

APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21926

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P06804

Gene Symbols

Tnf

Immunogen

E.coli-derived, 17.3 kDa Recombinant Murine TNF-alpha

Quantity

500μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine TNF-alpha
  • Anti-Murine TNF-alpha-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Murine TNF-alpha by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine TNF-alpha (500-P64) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine TNF-alpha
  • Western Blot: To detect Murine TNF-alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine TNF-alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P64BT-1MG will be provided as 2 x 500 μg TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

Show Difference

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Fischer Scientific

50-271-8464

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Antigen:
TNF alpha

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21926

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P06804

Gene Symbols:
Tnf

Immunogen:
E.coli-derived, 17.3 kDa Recombinant Murine TNF-alpha

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

Fischer Scientific

50-271-8465

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Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21943

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35235

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

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50-271-8467

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Antigen:
MCP-5

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Ccl12

Gene Alias:
C-C motif chemokine 12; Ccl12; chemokine (C-C motif) ligand 12; MCP-1-related chemokine; Mcp5; MCP-5; Monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya12; small inducible cytokine A12; small-inducible cytokine A12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20293

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q62401

Gene Symbols:
Ccl12

Immunogen:
E.coli-derived Recombinant Murine MCP-5 (CCL12)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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50-271-8468

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Antigen:
IL-10

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL10

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16153

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P18893

Gene Symbols:
IL10

Immunogen:
E.coli-derived Recombinant Murine IL-10

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized