50-271-8465

RANKL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-271-8465-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8465 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

RANKL (soluble)

Classification

Polyclonal

Conjugate

Biotin

Gene

TNFSF11

Gene Alias

CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21943

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O35235

Gene Symbols

TNFSF11

Immunogen

E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity

500μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: PAMMEGSWLD VAQRGKPEAQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine sRANK Ligand
  • Anti-Murine sRANK Ligand-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect msRANKL by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine sRANKL (500-P63) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant msRANKL
  • Western Blot: To detect msRANKL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 mg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant msRANKL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P63BT-1MG will be provided as 2 x 500 μg This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
  • This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
  • T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
  • This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
  • Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
  • The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
  • Two alternatively spliced transcript variants have been found.

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Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21943

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35235

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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50-271-8467

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Antigen:
MCP-5

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Ccl12

Gene Alias:
C-C motif chemokine 12; Ccl12; chemokine (C-C motif) ligand 12; MCP-1-related chemokine; Mcp5; MCP-5; Monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya12; small inducible cytokine A12; small-inducible cytokine A12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20293

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q62401

Gene Symbols:
Ccl12

Immunogen:
E.coli-derived Recombinant Murine MCP-5 (CCL12)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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50-271-8468

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Antigen:
IL-10

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL10

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16153

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P18893

Gene Symbols:
IL10

Immunogen:
E.coli-derived Recombinant Murine IL-10

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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Antigen:
IL-9

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Il9

Gene Alias:
cytokine P40; homolog of mouse T cell and mast cell growth factor 40; HP40; IL9; IL-9; ILN; Interleukin; interleukin 9; Interleukin9; interleukin-9; P40; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16198

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P15247

Gene Symbols:
Il9

Immunogen:
E.coli-derived Recombinant Murine IL-9

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized