50-271-8679

RANKL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-271-8679-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8679 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

RANKL (soluble)

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

O14788

Gene Symbols

TNFSF11

Immunogen

E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG

Applications

Western Blot, ELISA

Conjugate

Biotin

Gene

TNFSF11

Gene Alias

CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8600

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: MEKAMVDGSW LDLAKRSKLE AQPFAHLTIN ATDIPSGSHK VSLSSWYHDR GWAKISNMTF SNGKLIVNQD GFYYLYANIC FRHHETSGDL ATEYLQLMVY VTKTSIKIPS SHTLMKGGST KYWSGNSEFH FYSINVGGFF KLRSGEEISI EVSNPSLLDP DQDATYFGAF KVRDID
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Human sRANK Ligand
  • Anti-Human sRANK Ligand-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human sRANK Ligand by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sRANK Ligand (500-P133G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sRANK Ligand
  • Western Blot: To detect hsRANKL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hsRANKL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P133GBT-1MG will be provided as 2 x 500 μg This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
  • This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
  • T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
  • This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
  • Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
  • The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
  • Two alternatively spliced transcript variants have been found.

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Fischer Scientific

50-271-8679

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Antigen:
RANKL (soluble)

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
O14788

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8600

Form:
Lyophilized

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50-271-8682

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Antigen:
VEGF-165

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
Q00731

Gene Symbols:
Vegfa

Immunogen:
E.coli-derived, 39.0 kDa Recombinant Murine VEGF 165

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Isotype:
IgG

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
Vegfa

Gene Alias:
H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22339

Form:
Lyophilized

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Fischer Scientific

50-271-8683

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Antigen:
CXCL2

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P10889

Gene Symbols:
Cxcl2

Immunogen:
E.coli-derived Recombinant Murine MIP-2 (CXCL2)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Isotype:
IgG

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
Cxcl2

Gene Alias:
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 2; CINC-2a; Cinc3; CINC-3; CXC; CXC motif chemokine; C-X-C motif chemokine 2; C-X-C motif chemokine ligand 2; CXCL; CXCL2; Cytokine-induced neutrophil chemoattractant 3; GRO b; gro beta; GRO β; GRO2; GRO2 oncogene; GROb; GRObeta; gro-beta; GRO-beta(5-73); GRO-beta-T; Growth-regulated protein beta; GROβ; Hematopoietic synergistic factor; HSF; Macrophage inflammatory protein 2; macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; Mgsa-b; MIP 2 a; MIP 2 alpha; MIP 2 a; Mip2; MIP-2; MIP2 a; MIP2 a; MIP2A; MIP-2a; MIP2-alpha; SB-251353; Scyb; Scyb2; small inducible cytokine subfamily, member 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20310

Form:
Lyophilized

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Antigen:
MCP-2

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
Q9Z121

Gene Symbols:
CCL8

Immunogen:
E.coli-derived Recombinant Murine MCP-2 (CCL8)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Isotype:
IgG

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
CCL8

Gene Alias:
1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20307

Form:
Lyophilized