50-271-8677

TRAIL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-271-8677-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8677 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

TRAIL (soluble)

Classification

Polyclonal

Conjugate

Biotin

Gene

TNFSF10

Gene Alias

A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8743

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P50591

Gene Symbols

TNFSF10

Immunogen

E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity

500μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Related Products

Img

Fischer Scientific

50-271-8527

--

Img

Fischer Scientific

50-271-8676

--

Img

Fischer Scientific

50-271-8465

--

Img

Fischer Scientific

50-271-8576

--

Img

Fischer Scientific

50-271-8679

--

Img

Fischer Scientific

50-271-8650

--

Img

Fischer Scientific

50-271-8635

--

Img

Fischer Scientific

50-271-8524

--

Description

  • AA Sequence of recombinant protein: MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sTRAIL/Apo2L
  • Anti-Human sTRAIL/Apo2L-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human sTRAIL/Apo2L by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sTRAIL/Apo2L (500-P135) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sTRAIL/Apo2L
  • Western Blot: To detect Human sTRAIL/Apo2L by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human sTRAIL/Apo2L is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P135BT-1MG will be provided as 2 x 500 μg TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
  • TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
  • TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
  • The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
  • The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
  • Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
  • TRAIL is a type II membrane protein and expressed in a variety of human tissues
  • Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-271-8677

--


Antigen:
TRAIL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

50-271-8679

--


Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8600

Content And Storage:
__

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
O14788

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

50-271-8682

--


Antigen:
VEGF-165

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Vegfa

Gene Alias:
H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22339

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q00731

Gene Symbols:
Vegfa

Immunogen:
E.coli-derived, 39.0 kDa Recombinant Murine VEGF 165

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

Fischer Scientific

50-271-8683

--


Antigen:
CXCL2

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Cxcl2

Gene Alias:
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 2; CINC-2a; Cinc3; CINC-3; CXC; CXC motif chemokine; C-X-C motif chemokine 2; C-X-C motif chemokine ligand 2; CXCL; CXCL2; Cytokine-induced neutrophil chemoattractant 3; GRO b; gro beta; GRO β; GRO2; GRO2 oncogene; GROb; GRObeta; gro-beta; GRO-beta(5-73); GRO-beta-T; Growth-regulated protein beta; GROβ; Hematopoietic synergistic factor; HSF; Macrophage inflammatory protein 2; macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; Mgsa-b; MIP 2 a; MIP 2 alpha; MIP 2 a; Mip2; MIP-2; MIP2 a; MIP2 a; MIP2A; MIP-2a; MIP2-alpha; SB-251353; Scyb; Scyb2; small inducible cytokine subfamily, member 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20310

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P10889

Gene Symbols:
Cxcl2

Immunogen:
E.coli-derived Recombinant Murine MIP-2 (CXCL2)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized