50-271-8530
TRAIL-R2 (DR5) (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8530-Each-of-1 | In Stock | ₹ 1,68,767.10 |
50-271-8530 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,68,767.10
GST (18%): ₹ 30,378.078
Total Price: ₹ 1,99,145.178
Antigen
TRAIL-R2 (DR5) (soluble)
Classification
Polyclonal
Conjugate
Biotin
Gene
TNFRSF10B
Gene Alias
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8795
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
O14763
Gene Symbols
TNFRSF10B
Immunogen
E.coli-derived, 14.9 kDa Recombinant Human sTRAIL Receptor-2
Quantity
500μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
Related Products
Description
- AA Sequence of recombinant protein: MESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sTRAIL Receptor-2
- Anti-Human sTRAIL Receptor-2-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect hsTRAIL Receptor-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sTRAIL Receptor-2 (500-P299) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hsTRAIL Receptor-2
- Western Blot: To detect hsTRAIL Receptor-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hsTRAIL Receptor-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P299BT-1MG will be provided as 2 x 500 μg DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
- DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
- DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
- Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
- Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
- Overexpression of DR5 induces apoptosis and activates NF-kappa-B
- DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
- Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.
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Antigen: TRAIL-R2 (DR5) (soluble)
Classification: Polyclonal
Conjugate: Biotin
Gene: TNFRSF10B
Gene Alias: apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8795
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O14763
Gene Symbols: TNFRSF10B
Immunogen: E.coli-derived, 14.9 kDa Recombinant Human sTRAIL Receptor-2
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
TRAIL-R2 (DR5) (soluble)
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
TNFRSF10B
Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8795
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O14763
Gene Symbols:
TNFRSF10B
Immunogen:
E.coli-derived, 14.9 kDa Recombinant Human sTRAIL Receptor-2
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: CCL28
Classification: Polyclonal
Conjugate: Biotin
Gene: CCL28
Gene Alias: CC chemokine CCL28; C-C motif chemokine 28; C-C motif chemokine ligand 28; CCK 1; CCK1; CCK1 protein; CCL 28; Ccl28; chemokine (C-C motif) ligand 28; chemokine (C-C motif) ligand 28 splice variant chi; MEC; Mucosae-associated epithelial chemokine; Protein CCK1; SCYA28; small inducible cytokine A28; small inducible cytokine subfamily A (Cys-Cys), member 28; small-inducible cytokine A28
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56477
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9NRJ3
Gene Symbols: CCL28
Immunogen: E.coli-derived Recombinant Human MEC (CCL28)
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
CCL28
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
CCL28
Gene Alias:
CC chemokine CCL28; C-C motif chemokine 28; C-C motif chemokine ligand 28; CCK 1; CCK1; CCK1 protein; CCL 28; Ccl28; chemokine (C-C motif) ligand 28; chemokine (C-C motif) ligand 28 splice variant chi; MEC; Mucosae-associated epithelial chemokine; Protein CCK1; SCYA28; small inducible cytokine A28; small inducible cytokine subfamily A (Cys-Cys), member 28; small-inducible cytokine A28
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56477
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9NRJ3
Gene Symbols:
CCL28
Immunogen:
E.coli-derived Recombinant Human MEC (CCL28)
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: Klotho
Classification: Polyclonal
Conjugate: Biotin
Gene: KL
Gene Alias: alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9365
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9UEF7
Gene Symbols: KL
Immunogen: E.coli-derived Recombinant Human Klotho
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
Klotho
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
KL
Gene Alias:
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9365
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9UEF7
Gene Symbols:
KL
Immunogen:
E.coli-derived Recombinant Human Klotho
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: FAS (soluble)
Classification: Polyclonal
Conjugate: Biotin
Gene: FAS
Gene Alias: AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 355
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P25445
Gene Symbols: FAS
Immunogen: E.coli-derived Recombinant Human sFas Receptor
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
FAS (soluble)
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
FAS
Gene Alias:
AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
355
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P25445
Gene Symbols:
FAS
Immunogen:
E.coli-derived Recombinant Human sFas Receptor
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized