50-271-8554
IL-17A Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8554-Each-of-1 | In Stock | ₹ 1,68,767.10 |
50-271-8554 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,68,767.10
GST (18%): ₹ 30,378.078
Total Price: ₹ 1,99,145.178
Antigen
IL-17A
Classification
Polyclonal
Conjugate
Biotin
Gene
IL17A
Gene Alias
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16171
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q62386
Gene Symbols
IL17A
Immunogen
E.coli-derived Recombinant Murine IL-17A
Quantity
500μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Lyophilized
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Description
- AA Sequence of recombinant protein: AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV GCTCVASIVR QAA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-17A
- Anti-Murine IL-17A-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect mIL-17A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-17A (500-P265) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mIL-17A
- Western Blot: To detect mIL-17A by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P265BT-1MG will be provided as 2 x 500 μg Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
- IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
- High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
- In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
- In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
- Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
- IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).
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Show Difference
Antigen: IL-17A
Classification: Polyclonal
Conjugate: Biotin
Gene: IL17A
Gene Alias: Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16171
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q62386
Gene Symbols: IL17A
Immunogen: E.coli-derived Recombinant Murine IL-17A
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Lyophilized
Antigen:
IL-17A
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
IL17A
Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16171
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q62386
Gene Symbols:
IL17A
Immunogen:
E.coli-derived Recombinant Murine IL-17A
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Lyophilized
Antigen: Endostatin
Classification: Polyclonal
Conjugate: Biotin
Gene: COL18A1
Gene Alias: antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80781
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P39060
Gene Symbols: COL18A1
Immunogen: E.coli-derived Recombinant Human Endostatin
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
Endostatin
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
COL18A1
Gene Alias:
antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80781
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P39060
Gene Symbols:
COL18A1
Immunogen:
E.coli-derived Recombinant Human Endostatin
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: PAI1
Classification: Polyclonal
Conjugate: Biotin
Gene: Serpine1
Gene Alias: Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5054
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P05121
Gene Symbols: Serpine1
Immunogen: E.coli-derived, 42.7 kDa Recombinant Human PAI-1
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
PAI1
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
Serpine1
Gene Alias:
Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5054
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P05121
Gene Symbols:
Serpine1
Immunogen:
E.coli-derived, 42.7 kDa Recombinant Human PAI-1
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: IL-5
Classification: Polyclonal
Conjugate: Biotin
Gene: Il5
Gene Alias: B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3567
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P05113
Gene Symbols: Il5
Immunogen: E.coli-derived Recombinant Human IL-5
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
IL-5
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
Il5
Gene Alias:
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3567
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P05113
Gene Symbols:
Il5
Immunogen:
E.coli-derived Recombinant Human IL-5
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized