50-271-8718

IL-17A Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-271-8718-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8718 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

IL-17A

Classification

Polyclonal

Conjugate

Biotin

Gene

IL17A

Gene Alias

Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q16552

Gene Symbols

IL17A

Immunogen

E.coli-derived Recombinant Human IL-17A

Quantity

500μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-17A
  • Anti-Human IL-17A-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human IL-17A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IL-17A (500-P07) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IL-17A
  • Western Blot: To detect hIL-17A by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P07BT-1MG will be provided as 2 x 500 μg Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

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Fischer Scientific

50-271-8718

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Antigen:
IL-17A

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Immunogen:
E.coli-derived Recombinant Human IL-17A

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

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50-271-8719

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Antigen:
IL-16

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL16

Gene Alias:
FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3603

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q14005

Gene Symbols:
IL16

Immunogen:
E.coli-derived Recombinant Human IL-16 (129 a.a.)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

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50-271-8721

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Antigen:
MCP-4

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
CCL13

Gene Alias:
C-C motif chemokine 13; C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain; C-C motif chemokine ligand 13; CCL 13; CCL13; chemokine (C-C motif) ligand 13; CKb10; CK-beta-10; H-MCP-4; MCP4; MCP-4; Monocyte chemoattractant protein 4; monocyte chemotactic protein 4; NCC1; NCC-1; new CC chemokine 1; SCYA13; SCYL1; small inducible cytokine subfamily A (Cys-Cys), member 13; small-inducible cytokine A13

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6357

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q99616

Gene Symbols:
CCL13

Immunogen:
E.coli-derived Recombinant Human MCP-4 (CCL13)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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50-271-8723

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Antigen:
PPBP

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
PPBP

Gene Alias:
2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB;

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5473

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P02775

Gene Symbols:
PPBP

Immunogen:
E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized