50-271-8645

4-1BB Ligand Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-271-8645-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8645 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

4-1BB Ligand

Classification

Polyclonal

Conjugate

Biotin

Gene

TNFSF9

Gene Alias

4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8744

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P41273

Gene Symbols

TNFSF9

Immunogen

E.coli-derived Recombinant Human 4-1BB Ligand

Quantity

500μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human 4-1BB Ligand
  • Anti-Human 4-1BB Ligand-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect h4-1BBL by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human 4-1BBL (500-P169) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant h4-1BBL
  • Western Blot: To detect h4-1BBL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant h4-1BBL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P169BT-1MG will be provided as 2 x 500 μg CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily
  • CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation
  • Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes
  • Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity
  • CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma)
  • CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.

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Antigen:
4-1BB Ligand

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF9

Gene Alias:
4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8744

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41273

Gene Symbols:
TNFSF9

Immunogen:
E.coli-derived Recombinant Human 4-1BB Ligand

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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Antigen:
TNFR2 (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Tnfrsf1b

Gene Alias:
CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7133

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P20333

Gene Symbols:
Tnfrsf1b

Immunogen:
E.coli-derived, 18.9 kDa Recombinant Human TNF Receptor Type II

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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Antigen:
CD137

Classification:
Polyclonal

Conjugate:
__

Gene:
TNFRSF9

Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3604

Content And Storage:
__

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
Q07011

Gene Symbols:
TNFRSF9

Immunogen:
E.coli-derived Recombinant Human 4-1BB Receptor

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
__

Form:
Lyophilized

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Antigen:
CD267 (TACI)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFRSF13B

Gene Alias:
1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23495

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O14836

Gene Symbols:
TNFRSF13B

Immunogen:
E.coli-derived, 17.8 kDa Recombinant Human TACI

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized