500P11BT25

IGF1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 500P11BT25-Each-of-1 In Stock ₹ 19,422.12

500P11BT25 - Each of 1

₹ 19,422.12

In Stock

Quantity

1

Base Price: ₹ 19,422.12

GST (18%): ₹ 3,495.982

Total Price: ₹ 22,918.102

Antigen

IGF1

Classification

Polyclonal

Conjugate

Biotin

Gene

IGF1

Gene Alias

C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3479

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P05019

Gene Symbols

IGF1

Immunogen

E.coli-derived Recombinant Human IGF-I

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-I
  • Anti-Human IGF-I-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human IGF-I by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-I (500-P11) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-I
  • Western Blot: To detect hIGF-I by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-I is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P11BT-1MG will be provided as 2 x 500 μg IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer's disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

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Show Difference

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Fischer Scientific

500P11BT25

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Antigen:
IGF1

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IGF1

Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
E.coli-derived Recombinant Human IGF-I

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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500P11BT50

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Antigen:
IGF1

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IGF1

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
E.coli-derived Recombinant Human IGF-I

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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500P121BT1

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Antigen:
CCL3

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Ccl3

Gene Alias:
AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1a; MIP-1alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20302

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P10855

Gene Symbols:
Ccl3

Immunogen:
E.coli-derived Recombinant Murine MIP-1alpha (CCL3)

Quantity:
2 x 500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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500P121BT25

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Antigen:
CCL3

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Ccl3

Gene Alias:
AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1a; MIP-1alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20302

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P10855

Gene Symbols:
Ccl3

Immunogen:
E.coli-derived Recombinant Murine MIP-1alpha (CCL3)

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized