500P86100UG

Leptin Polyclonal Antibody, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 500P86100UG-Each-of-1 In Stock ₹ 24,812.40

500P86100UG - Each of 1

₹ 24,812.40

In Stock

Quantity

1

Base Price: ₹ 24,812.40

GST (18%): ₹ 4,466.232

Total Price: ₹ 29,278.632

Antigen

Leptin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Lep

Gene Alias

CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3952

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P41159

Gene Symbols

Lep

Immunogen

E.coli-derived Recombinant Human Leptin

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Leptin
  • Anti-Human Leptin-specific antibody was purified by affinity chromatography employing an immobilized Human Leptin matrix
  • Sandwich ELISA: To detect Human Leptin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human Leptin (500-P86Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Leptin
  • Western Blot: To detect Human Leptin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Leptin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
  • Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
  • Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
  • Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
  • Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
  • Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
  • Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
  • Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
  • Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
  • Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
  • Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.

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Show Difference

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Fischer Scientific

500P86100UG

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Antigen:
Leptin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
E.coli-derived Recombinant Human Leptin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P8650UG

--


Antigen:
Leptin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
E.coli-derived Recombinant Human Leptin

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P86BT1MG

--


Antigen:
Leptin

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
E.coli-derived Recombinant Human Leptin

Quantity:
2 x 500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P86BT25

--


Antigen:
Leptin

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
E.coli-derived Recombinant Human Leptin

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized