51-033-182

CD33 Monoclonal Antibody (9A11-CD33), Alexa Fluor™ 647, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 51-033-182-Each-of-1 In Stock ₹ 15,144.12

51-033-182 - Each of 1

₹ 15,144.12

In Stock

Quantity

1

Base Price: ₹ 15,144.12

GST (18%): ₹ 2,725.942

Total Price: ₹ 17,870.062

Antigen

CD33

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.

Q63994

Gene Symbols

CD33

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12489

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

9A11-CD33

Conjugate

Alexa Fluor 647

Gene

CD33

Gene Alias

CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: This monoclonal antibody 9A11-CD33 reacts with mouse CD33, also known as Siglec3 and gp67
  • CD33 belongs to the sialic acid-binding immunoglobulin lectins (Siglec) family that binds to sialic acid-containing glycans on cell surface glycoproteins and glycolipids on mammalian cells
  • Mouse CD33 binds to short O-linked glycans of certain mucins and sialyl-Tn epitopes
  • Mouse CD33 is expressed by mature granulocytes, immature myeloid cells, and microglia
  • Unlike human CD33, mouse CD33 lacks a cytoplasmic ITIM domain and exists as two splice variants that have different cytoplasmic tails
  • In microglia, CD33 inhibits the phagocytosis of toxic amyloid beta
  • Clone 9A11 has been used to characterize mouse CD33 surface expression and function
  • <a href=https://www.ncbi.nlm.nih.gov/pubmed/31925286>View Article</a>
  • Applications Reported: This 9A11-CD33 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 9A11-CD33 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This may be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family
  • It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface
  • CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia
  • Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells
  • CD33 is also expressed on, and is a useful marker for, peripheral monocytes
  • CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias
  • Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.

Compare Similar Items

Show Difference

Img

Fischer Scientific

51-033-182

--


Antigen:
CD33

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q63994

Gene Symbols:
CD33

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12489

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
9A11-CD33

Conjugate:
Alexa Fluor 647

Gene:
CD33

Gene Alias:
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

51-045-942

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Antigen:
CD45

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HI30

Conjugate:
Alexa Fluor 647

Gene:
PTPRC

Gene Alias:
B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

51-050-0

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Antigen:
NFkB p65

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q04206, Q04207

Gene Symbols:
RELA

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19697, 5970

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

51-070-0

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Antigen:
14-3-3 Pan

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O70456, P27348, P31946, P31947, P35213, P61981, P61982, P61983, P62258, P62259, P62260, P62261, P63101, P63102, P63103, P63104, P68250, P68252, P68254, P68255, Q0VC36, Q3SZI4, Q52M98, Q5XHK2, Q6NRY9, Q6PCG0, Q8AVQ3, Q9CQV8

Gene Symbols:
Sfn, YWHAB, ywhab.L, ywhab.S, YWHAE, YWHAG, ywhag.L, ywhag.S, YWHAQ, YWHAZ

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100505434, 10971, 22627, 22628, 22630, 22631, 25577, 25578, 2810, 282125, 286862, 286863, 287022, 29753, 313017, 379724, 380457, 399276, 432005, 528453, 54401, 55948, 56010, 56011, 7529, 7531, 7532, 7534, 768311

Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
YWHAZ

Gene Alias:
1110013I11Rik; 1300003C17Rik; 14-3-3; 14-3-3 alpha; 14-3-3 beta; 14-3-3 delta; 14-3-3 epsilon; 14-3-3 gamma; 14-3-3 protein beta; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha, N-terminally processed; 14-3-3 protein beta/alpha-A; 14-3-3 protein beta/alpha-B; 14-3-3 protein beta-subtype; 14-3-3 protein epsilon; 14-3-3 protein gamma; 14-3-3 protein gamma subtype; 14-3-3 protein gamma, N-terminally processed; 14-3-3 protein gamma-A; 14-3-3 protein gamma-B; 14-3-3 protein gamma-subtype; 14-3-3 protein sigma; 14-3-3 protein tau; 14-3-3 protein T-cell; 14-3-3 protein theta; 14-3-3 protein zeta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 sigma; 14-3-3 sigma protein; 14-3-3 tau; 14-3-3 theta; 14-3-3 zeta; 14-3-3beta; 14-3-3d; 14-3-3E; 14-3-3G; 14-3-3gamma; 14-3-3-like protein; 14-3-3t; 14-3-3z; 14-3-3zeta; 14-3-3-zeta; 1C5; 2700028P07Rik; 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide; 3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; AA409740; AI596267; AL022924; AU019196; AU020854; AU021156; brain protein 14-3-3, beta isoform; D7Bwg1348e; epididymis luminal protein 2; epididymis luminal protein 4; epididymis secretory protein Li 1; epididymis secretory protein Li 3; epididymis secretory protein Li 93; epithelial cell marker protein 1; Er; factor activating exoenzyme S; FAS; GW128; HEL2; HEL4; HEL-S-1; HEL-S-3; HEL-S-93; HME1; HS1; KCIP-1; MDCR; MDS; mitochondrial import stimulation factor (MSF) L subunit; mitochondrial import stimulation factor L subunit; Mitochondrial import stimulation factor S1 subunit; Mkrn3; Mme1; MSF L; Msfs1; phospholipase A2; PPP1R170; prepronerve growth factor RNH-1; Protein 1054; Protein HS1; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; protein phosphatase 1, regulatory subunit 170; protein tau; protein, theta; R74690; SEZ-2; SFN; Stratifin; tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma; tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma L homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma S homeolog

Host Species:
Rabbit

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG