51-045-942

CD45 Monoclonal Antibody (HI30), Alexa Fluor™ 647, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 51-045-942-Each-of-1 In Stock ₹ 23,272.32

51-045-942 - Each of 1

₹ 23,272.32

In Stock

Quantity

1

Base Price: ₹ 23,272.32

GST (18%): ₹ 4,189.018

Total Price: ₹ 27,461.338

Antigen

CD45

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P08575

Gene Symbols

PTPRC

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

HI30

Conjugate

Alexa Fluor 647

Gene

PTPRC

Gene Alias

B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The HI30 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA)
  • CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets
  • The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes
  • Applications Reported: This HI30 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This HI30 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
  • This may be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

Img

Invitrogen

51-045-942

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HI30

Conjugate:
Alexa Fluor 647

Gene:
PTPRC

Gene Alias:
B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

51-050-0

--


Antigen:
NFkB p65

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q04206, Q04207

Gene Symbols:
RELA

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19697, 5970

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

51-070-0

--


Antigen:
14-3-3 Pan

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O70456, P27348, P31946, P31947, P35213, P61981, P61982, P61983, P62258, P62259, P62260, P62261, P63101, P63102, P63103, P63104, P68250, P68252, P68254, P68255, Q0VC36, Q3SZI4, Q52M98, Q5XHK2, Q6NRY9, Q6PCG0, Q8AVQ3, Q9CQV8

Gene Symbols:
Sfn, YWHAB, ywhab.L, ywhab.S, YWHAE, YWHAG, ywhag.L, ywhag.S, YWHAQ, YWHAZ

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100505434, 10971, 22627, 22628, 22630, 22631, 25577, 25578, 2810, 282125, 286862, 286863, 287022, 29753, 313017, 379724, 380457, 399276, 432005, 528453, 54401, 55948, 56010, 56011, 7529, 7531, 7532, 7534, 768311

Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
YWHAZ

Gene Alias:
1110013I11Rik; 1300003C17Rik; 14-3-3; 14-3-3 alpha; 14-3-3 beta; 14-3-3 delta; 14-3-3 epsilon; 14-3-3 gamma; 14-3-3 protein beta; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha, N-terminally processed; 14-3-3 protein beta/alpha-A; 14-3-3 protein beta/alpha-B; 14-3-3 protein beta-subtype; 14-3-3 protein epsilon; 14-3-3 protein gamma; 14-3-3 protein gamma subtype; 14-3-3 protein gamma, N-terminally processed; 14-3-3 protein gamma-A; 14-3-3 protein gamma-B; 14-3-3 protein gamma-subtype; 14-3-3 protein sigma; 14-3-3 protein tau; 14-3-3 protein T-cell; 14-3-3 protein theta; 14-3-3 protein zeta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 sigma; 14-3-3 sigma protein; 14-3-3 tau; 14-3-3 theta; 14-3-3 zeta; 14-3-3beta; 14-3-3d; 14-3-3E; 14-3-3G; 14-3-3gamma; 14-3-3-like protein; 14-3-3t; 14-3-3z; 14-3-3zeta; 14-3-3-zeta; 1C5; 2700028P07Rik; 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide; 3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; AA409740; AI596267; AL022924; AU019196; AU020854; AU021156; brain protein 14-3-3, beta isoform; D7Bwg1348e; epididymis luminal protein 2; epididymis luminal protein 4; epididymis secretory protein Li 1; epididymis secretory protein Li 3; epididymis secretory protein Li 93; epithelial cell marker protein 1; Er; factor activating exoenzyme S; FAS; GW128; HEL2; HEL4; HEL-S-1; HEL-S-3; HEL-S-93; HME1; HS1; KCIP-1; MDCR; MDS; mitochondrial import stimulation factor (MSF) L subunit; mitochondrial import stimulation factor L subunit; Mitochondrial import stimulation factor S1 subunit; Mkrn3; Mme1; MSF L; Msfs1; phospholipase A2; PPP1R170; prepronerve growth factor RNH-1; Protein 1054; Protein HS1; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; protein phosphatase 1, regulatory subunit 170; protein tau; protein, theta; R74690; SEZ-2; SFN; Stratifin; tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma; tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma L homeolog; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma S homeolog

Host Species:
Rabbit

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

51-088-842

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Antigen:
CD88 (C5aR1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21730

Gene Symbols:
C5AR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
S5/1

Conjugate:
Alexa Fluor 647

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ