51-950-042

TIGIT Monoclonal Antibody (MBSA43), Alexa Fluor™ 647, eBioscience™, Invitrogen™

Manufacturer: eBioscience

Select a Size

Pack Size SKU Availability Price
Each of 1 51-950-042-Each-of-1 In Stock ₹ 37,218.60

51-950-042 - Each of 1

₹ 37,218.60

In Stock

Quantity

1

Base Price: ₹ 37,218.60

GST (18%): ₹ 6,699.348

Total Price: ₹ 43,917.948

Antigen

TIGIT

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q495A1

Gene Symbols

TIGIT

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

201633

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

MBSA43

Conjugate

Alexa Fluor 647

Gene

TIGIT

Gene Alias

ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM
  • This 26 kDa protein is a member of the poliovirus receptor (PVR) family
  • The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naive CD4+ T cells
  • TIGIT may be upregulated on naive CD4+ T cells upon activation
  • TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins
  • MBSA43 is reported to crossreact with Rhesus macaque
  • Applications Reported: This MBSA43 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This MBSA43 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
  • This may be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Compare Similar Items

Show Difference

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eBioscience

51-950-042

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Antigen:
TIGIT

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q495A1

Gene Symbols:
TIGIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201633

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MBSA43

Conjugate:
Alexa Fluor 647

Gene:
TIGIT

Gene Alias:
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
COX2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P35354

Gene Symbols:
PTGS2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5743

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
COX 229

Conjugate:
Alexa Fluor 647

Gene:
PTGS2

Gene Alias:
COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

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Antigen:
Sall1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9ER74

Gene Symbols:
SALL1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58198

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
NRNSTNX

Conjugate:
Alexa Fluor 647

Gene:
SALL1

Gene Alias:
epididymis secretory protein Li 89; HEL-S-89; HSal1; Msal-3; SAL1; Sal-1; sal-3; SALL1; sal-like 1; sal-like 1 (Drosophila); sal-like protein 1; spalt like transcription factor 1; spalt-like transcription factor 1; TBS; Zinc finger protein 794; zinc finger protein SALL1; Zinc finger protein Spalt-1; zinc finger protein Spalt-3; ZNF794

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

51-972-982

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Antigen:
Sall1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9ER74

Gene Symbols:
SALL1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58198

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
NRNSTNX

Conjugate:
Alexa Fluor 647

Gene:
SALL1

Gene Alias:
epididymis secretory protein Li 89; HEL-S-89; HSal1; Msal-3; SAL1; Sal-1; sal-3; SALL1; sal-like 1; sal-like 1 (Drosophila); sal-like protein 1; spalt like transcription factor 1; spalt-like transcription factor 1; TBS; Zinc finger protein 794; zinc finger protein SALL1; Zinc finger protein Spalt-1; zinc finger protein Spalt-3; ZNF794

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ