CD66 Monoclonal Antibody (CD66a-B1.1), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-066-842-Each-of-1 | In Stock | ₹ 29,175.96 |
53-066-842 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,175.96
GST (18%): ₹ 5,251.673
Total Price: ₹ 34,427.633
Antigen
CD66
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
O75871, P06731, P13688, P40198, P40199
Gene Symbols
CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1048, 1084, 1089, 4680, 634
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
CD66a-B1.1
Conjugate
Alexa Fluor 488
Gene
CEACAM4
Gene Alias
antigen CD66, BGP, BGP1, BGP-1, BGPI, Biliary glycoprotein 1, Carcinoembryonic antigen, Carcinoembryonic antigen CGM1, carcinoembryonic antigen CGM7, carcinoembryonic antigen gene family member 1, carcinoembryonic antigen gene family member 7, carcinoembryonic antigen related cell adhesion molecule 1, carcinoembryonic antigen related cell adhesion molecule 3, carcinoembryonic antigen related cell adhesion molecule 4, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen related cell adhesion molecule 6, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen-related cell adhesion molecule 4, carcinoembryonic antigen-related cell adhesion molecule 4-sv1, carcinoembryonic antigen-related cell adhesion molecule 4-sv2, carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen-related cell adhesion molecule 6, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen), CD66a, CD66a antigen, CD66c, CD66d, CD66d antigen, CD66e, CEA, CEACAM1, CEACAM-1, CEACAM3, CEACAM-3, CEACAM4, CEACAM5, CEACAM-5, CEACAM6, CEACAM-6, CEAL, CGM1, CGM7, CGM7_HUMAN, Cluster of Differentiation 66c, meconium antigen 100, NCA, Non-specific crossreacting antigen, nonspecific cross-reacting antigen, Nonspecific cross-reacting antigen (NCA), non-specific cross-reacting antigen W236, nonspecific cross-reacting antigen W236, normal cross-reacting antigen, pan CEACAM, W264, W282
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively
- CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes
- Myeloma and cancer cells also express CD66
- Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells
- CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells
- CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling
- Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically
- Applications Reported: This CD66A-B1.1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This CD66A-B1.1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family
- They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells
- The expression of CD66 increases significantly on granulocytes upon their activation
- CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.
Compare Similar Items
Show Difference
Antigen: CD66
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: O75871, P06731, P13688, P40198, P40199
Gene Symbols: CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1048, 1084, 1089, 4680, 634
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CD66a-B1.1
Conjugate: Alexa Fluor 488
Gene: CEACAM4
Gene Alias: antigen CD66, BGP, BGP1, BGP-1, BGPI, Biliary glycoprotein 1, Carcinoembryonic antigen, Carcinoembryonic antigen CGM1, carcinoembryonic antigen CGM7, carcinoembryonic antigen gene family member 1, carcinoembryonic antigen gene family member 7, carcinoembryonic antigen related cell adhesion molecule 1, carcinoembryonic antigen related cell adhesion molecule 3, carcinoembryonic antigen related cell adhesion molecule 4, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen related cell adhesion molecule 6, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen-related cell adhesion molecule 4, carcinoembryonic antigen-related cell adhesion molecule 4-sv1, carcinoembryonic antigen-related cell adhesion molecule 4-sv2, carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen-related cell adhesion molecule 6, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen), CD66a, CD66a antigen, CD66c, CD66d, CD66d antigen, CD66e, CEA, CEACAM1, CEACAM-1, CEACAM3, CEACAM-3, CEACAM4, CEACAM5, CEACAM-5, CEACAM6, CEACAM-6, CEAL, CGM1, CGM7, CGM7_HUMAN, Cluster of Differentiation 66c, meconium antigen 100, NCA, Non-specific crossreacting antigen, nonspecific cross-reacting antigen, Nonspecific cross-reacting antigen (NCA), non-specific cross-reacting antigen W236, nonspecific cross-reacting antigen W236, normal cross-reacting antigen, pan CEACAM, W264, W282
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen: CD68
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P31996
Gene Symbols: Cd68
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12514
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: FA-11
Conjugate: Alexa Fluor 488
Gene: Cd68
Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species: Rat
Quantity: 25μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen: CD68
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P31996
Gene Symbols: Cd68
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12514
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: FA-11
Conjugate: Alexa Fluor 488
Gene: Cd68
Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
