53-611-982
Tmem119 Monoclonal Antibody (V3RT1GOsz), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-611-982-Each-of-1 | In Stock | ₹ 37,646.40 |
53-611-982 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,646.40
GST (18%): ₹ 6,776.352
Total Price: ₹ 44,422.752
Antigen
Tmem119
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q8R138
Gene Symbols
TMEM119
Immunogen
cell surface peptide
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
V3RT1GOsz
Conjugate
Alexa Fluor 488
Gene
TMEM119
Gene Alias
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species
Rat
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
231633
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- Description: This V3RT1GOsz monoclonal antibody recognizes mouse Tmem119
- This clone has been reported to be successfully used in flow cytometry
- Applications Reported: This V3RT1GOsz antibody has been reported for use in flow cytometric analysis
- Applications Tested: This V3RT1GOsz antibody has been tested by flow cytometric analysis of mouse brain cells after myelin removal
- This may be used at less than or equal to 1.0 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser Tmem119 encodes a single-pass type I transmembrane protein which seems to interact with a multitude of micro-RNAs as well as certain transcription factors such as SMAD1, SMAD5 and RUNX2
- Tmem119 has been identified as a surface marker of microglia that can be used to reliably distinguish microglia from infiltrating macrophages
- Microglial cells are phagocytes that are restricted to the brain and involved in clearing up debris and dendrite pruning of neurons
- They display a high functional plasticity, balancing neuroprotective and neurotoxic functions, which is reflected by their distinct physiology in response to changes in their microenvironment
- Microglia are particularly mobile in areas of the brain undergoing restructuring
- Reactive microglia co-express the marker Iba1
- In a pathological context, microglia have been associated with differentiation of pathogenic/inflammatory A1 type astrocytes by secretion of Cq1, IL-1a and TNF when stimulated with LPS, and thought to contribute to the pathology of several neurodegenerative diseases such as Alzheimers, Parkinsons, Chorea Huntingtons disease and Multiple Sclerosis
- The specific function Tmem119 plays on microglial cells remains unclear
- Outside of the neural system, Tmem119 seems to be involved in osteoblast differentiation/ossification.
Compare Similar Items
Show Difference
Antigen: Tmem119
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q8R138
Gene Symbols: TMEM119
Immunogen: cell surface peptide
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: V3RT1GOsz
Conjugate: Alexa Fluor 488
Gene: TMEM119
Gene Alias: AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231633
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Tmem119
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q8R138
Gene Symbols:
TMEM119
Immunogen:
cell surface peptide
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
V3RT1GOsz
Conjugate:
Alexa Fluor 488
Gene:
TMEM119
Gene Alias:
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231633
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Glucocorticoid receptor (NR3C1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P06537
Gene Symbols: Nr3c1
Immunogen: Partially purified rat GR
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: BuGR2
Conjugate: Alexa Fluor 488
Gene: Nr3c1
Gene Alias: cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14815
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Glucocorticoid receptor (NR3C1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P06537
Gene Symbols:
Nr3c1
Immunogen:
Partially purified rat GR
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
BuGR2
Conjugate:
Alexa Fluor 488
Gene:
Nr3c1
Gene Alias:
cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14815
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Glucocorticoid receptor (NR3C1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P06537
Gene Symbols: Nr3c1
Immunogen: Partially purified rat GR
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: BuGR2
Conjugate: Alexa Fluor 488
Gene: Nr3c1
Gene Alias: cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14815
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Glucocorticoid receptor (NR3C1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P06537
Gene Symbols:
Nr3c1
Immunogen:
Partially purified rat GR
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
BuGR2
Conjugate:
Alexa Fluor 488
Gene:
Nr3c1
Gene Alias:
cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14815
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: 10 mg
Primary or Secondary: __
Target Species: __
Product Type: NHI 2
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
10 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
NHI 2
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
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