Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Progesterone R/NR3C3
1.0 mg/mL
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Breast Cancer, Cancer
10mM PBS - BSA free with No Preservative
5241
A progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PR484
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
PGR
IgG1 κ
Protein G purified
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.