5323460
Progesterone R/NR3C3 Antibody (PR500), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Progesterone R/NR3C3
Concentration
0.2mg/mL
Applications
Western Blot, Immunohistochemistry (Paraffin), SDS-Page
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Breast Cancer, Cancer
Formulation
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez)
5241
Immunogen
progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Clone
PR500
Dilution
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Alias
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Gene Symbols
PGR
Isotype
IgG1 κ
Purification Method
Protein G purified
Test Specificity
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Description
- Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Progesterone R/NR3C3
Concentration: 0.2mg/mL
Applications: Western Blot, Immunohistochemistry (Paraffin), SDS-Page
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Breast Cancer, Cancer
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez): 5241
Immunogen: progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Clone: PR500
Dilution: Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Gene Symbols: PGR
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Antigen:
Progesterone R/NR3C3
Concentration:
0.2mg/mL
Applications:
Western Blot, Immunohistochemistry (Paraffin), SDS-Page
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Breast Cancer, Cancer
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez):
5241
Immunogen:
progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Clone:
PR500
Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Gene Symbols:
PGR
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Antigen: P-Selectin/CD62P
Concentration: 0.5 mg/mL
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Functional Assay
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: __
Formulation: Aqueous, may contain carrier protein/stabilizer. with 0.09% Sodium Azide
Gene ID (Entrez): 6403
Immunogen: The immunogen for this antibody was CD62P.
Primary or Secondary: Primary
Content And Storage: Store at 4C. Do not freeze.
Clone: AK-4
Dilution: Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Functional
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Target Species: Human
Gene Alias: CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Symbols: SELP
Isotype: IgG1 κ
Purification Method: Affinity Purified
Test Specificity: __
Antigen:
P-Selectin/CD62P
Concentration:
0.5 mg/mL
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Functional Assay
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
__
Formulation:
Aqueous, may contain carrier protein/stabilizer. with 0.09% Sodium Azide
Gene ID (Entrez):
6403
Immunogen:
The immunogen for this antibody was CD62P.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C. Do not freeze.
Clone:
AK-4
Dilution:
Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Functional
Classification:
Monoclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Symbols:
SELP
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Test Specificity:
__
Antigen: CD46
Concentration: 0.2mg/mL
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer, Cell Biology, Cellular Markers, Immunology
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez): 4179
Immunogen: A recombinant protein fragment specific for human CD46 was used as the immunogen.
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Clone: 122.2
Dilution: Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Gene Symbols: CD46
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Antigen:
CD46
Concentration:
0.2mg/mL
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez):
4179
Immunogen:
A recombinant protein fragment specific for human CD46 was used as the immunogen.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Clone:
122.2
Dilution:
Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Gene Symbols:
CD46
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Antigen: CD46
Concentration: 0.2mg/mL
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer, Cell Biology, Cellular Markers, Immunology
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez): 4179
Immunogen: A recombinant protein fragment specific for human CD46 was used as the immunogen.
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Clone: 122.2
Dilution: Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Gene Symbols: CD46
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Antigen:
CD46
Concentration:
0.2mg/mL
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene ID (Entrez):
4179
Immunogen:
A recombinant protein fragment specific for human CD46 was used as the immunogen.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Clone:
122.2
Dilution:
Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Gene Symbols:
CD46
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.