5349362
MilliporeSigma™ anti-CD11b FITC, Clone: M1/70,
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11b
Applications
Flow Cytometry
Conjugate
FITC
Host Species
Rat
Research Discipline
Inflammation, Immunology
Formulation
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Itgam
Isotype
IgG2b κ
Purification Method
Purified by size-exclusion chromatography
Clone
M1/70
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human, Mouse
Gene Accession No.
P05555
Immunogen
Proprietary immunogen
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
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Description
- Specifically detects CD11b Clone: M1/70 in Human, Mouse samples, and it is validated for Flow Cytometry The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M
- This 165-170kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g
- fibrinogen (cell-matrix)
- In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation
- Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed
- Integrin alphaM (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3)
- This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells
- The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.
Compare Similar Items
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Antigen: CD11b
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Itgam
Isotype: IgG2b κ
Purification Method: Purified by size-exclusion chromatography
Clone: M1/70
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P05555
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD11b
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Itgam
Isotype:
IgG2b κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
M1/70
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P05555
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD11b
Applications: Flow Cytometry
Conjugate: Red Fluor 710
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Itgam
Isotype: IgG2b κ
Purification Method: Purified by size-exclusion chromatography
Clone: M1/70
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P05555
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD11b
Applications:
Flow Cytometry
Conjugate:
Red Fluor 710
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Itgam
Isotype:
IgG2b κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
M1/70
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P05555
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD11c
Applications: Flow Cytometry
Conjugate: Red Fluor 710
Host Species: Armenian Hamster
Research Discipline: Inflammation, Immunology
Formulation: Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Itgax
Isotype: IgG
Purification Method: Purified by size-exclusion chromatography
Clone: N418
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: Q9QXH4
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD11c
Applications:
Flow Cytometry
Conjugate:
Red Fluor 710
Host Species:
Armenian Hamster
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Itgax
Isotype:
IgG
Purification Method:
Purified by size-exclusion chromatography
Clone:
N418
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
Q9QXH4
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD44
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Cd44, Ly-24
Isotype: IgG2b κ
Purification Method: Purified by size-exclusion chromatography
Clone: IM7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P15379
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD44
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Cd44, Ly-24
Isotype:
IgG2b κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
IM7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P15379
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze