5349364
MilliporeSigma™ anti-CD11c Red Fluor 710, Clone: N418,
Armenian Hamster Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11c
Applications
Flow Cytometry
Conjugate
Red Fluor 710
Host Species
Armenian Hamster
Research Discipline
Inflammation, Immunology
Formulation
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Itgax
Isotype
IgG
Purification Method
Purified by size-exclusion chromatography
Clone
N418
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Gene Accession No.
Q9QXH4
Immunogen
Proprietary immunogen
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
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Description
- Specifically detects CD11c Clone: N418 in Mouse samples, and it is validated for Flow Cytometry The N418 antibody reacts with mouse CD11c, also known as integrin alpha X
- This 150kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g
- fibrinogen (cell-matrix)
- In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation
- Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed
- Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The N418 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type
- CD11c is prominently expressed on tissue macrophages, and is also detected on some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).
Compare Similar Items
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Antigen: CD11c
Applications: Flow Cytometry
Conjugate: Red Fluor 710
Host Species: Armenian Hamster
Research Discipline: Inflammation, Immunology
Formulation: Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Itgax
Isotype: IgG
Purification Method: Purified by size-exclusion chromatography
Clone: N418
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: Q9QXH4
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD11c
Applications:
Flow Cytometry
Conjugate:
Red Fluor 710
Host Species:
Armenian Hamster
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Itgax
Isotype:
IgG
Purification Method:
Purified by size-exclusion chromatography
Clone:
N418
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
Q9QXH4
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD44
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Cd44, Ly-24
Isotype: IgG2b κ
Purification Method: Purified by size-exclusion chromatography
Clone: IM7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P15379
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD44
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Cd44, Ly-24
Isotype:
IgG2b κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
IM7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P15379
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD44
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Cd44, Ly-24
Isotype: IgG2b κ
Purification Method: Purified by size-exclusion chromatography
Clone: IM7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P15379
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD44
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Cd44, Ly-24
Isotype:
IgG2b κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
IM7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P15379
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: CD44
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Cd44, Ly-24
Isotype: __
Purification Method: Purified by size-exclusion chromatography
Clone: IM7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Accession No.: P15379
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD44
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Cd44, Ly-24
Isotype:
__
Purification Method:
Purified by size-exclusion chromatography
Clone:
IM7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Accession No.:
P15379
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze