3968634
CD11b/Mac-1 Mouse anti-Human, V450, Clone: ICRF44, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11b
Applications
Flow Cytometry
Conjugate
Violet Fluor 450 (V450)
Regulatory Status
RUO
Target Species
Human
Immunogen
Human monocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
ICRF44
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
Mac-1α, integrin αM subunit, CR3 α chain
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Description
- The ICRF44 monoclonal antibody reacts with CD11b, the 165kDa adhesion glycoprotein that associates with the 95kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
- CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
- CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
- This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
- The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm
- Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates
- Host Species: Mouse Clone: ICRF44 (also known as 44) Isotype: IgG1 κ Species Reactivity: Human Immunogen: Human monocytes Flow Cytometry
Compare Similar Items
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Antigen: CD11b
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Regulatory Status: RUO
Target Species: Human
Immunogen: Human monocytes
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: ICRF44
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: Mac-1α, integrin αM subunit, CR3 α chain
Antigen:
CD11b
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human monocytes
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
ICRF44
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
Mac-1α, integrin αM subunit, CR3 α chain
Antigen: CD11c
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Target Species: Mouse
Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: HL3
Classification: Monoclonal
Host Species: Hamster
Research Discipline: __
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: __
Purification Method: Affinity Purified
Description: Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
Antigen:
CD11c
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
HL3
Classification:
Monoclonal
Host Species:
Hamster
Research Discipline:
__
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
__
Purification Method:
Affinity Purified
Description:
Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
Antigen: CD11c
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Regulatory Status: RUO
Target Species: Human
Immunogen: Spleen Cells from Human with Hairy Cell Leukemia
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: B-LY6
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
Antigen:
CD11c
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Spleen Cells from Human with Hairy Cell Leukemia
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
B-LY6
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
Antigen: CD123
Applications: Flow Cytometry
Conjugate: PE-Cyanine5
Regulatory Status: RUO
Target Species: Human
Immunogen: Human IL-3Rα Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 9F5
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: IL-3 Receptor α chain
Antigen:
CD123
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine5
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human IL-3Rα Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
9F5
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
IL-3 Receptor α chain