5349416
MilliporeSigma™ anti-CD127 (IL-7Ra) Violer Fluor 450, Clone: A7R34,
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD127 (IL-7Ra)
Applications
Flow Cytometry
Conjugate
Violet Fluor 450 (V450)
Host Species
Rat
Research Discipline
Inflammation, Immunology
Formulation
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Il7r
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone
A7R34
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Gene Accession No.
P16872
Immunogen
Proprietary immunogen
Purification Method
Purified by size-exclusion chromatography
Description
- Specifically detects CD127 (IL-7Ra) Clone: A7R34 in Mouse samples, and it is validated for Flow Cytometry The A7R34 antibody is specific for mouse CD127, a 60-90kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha
- CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132)
- This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis
- A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells
- CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).
Compare Similar Items
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Antigen: CD127 (IL-7Ra)
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Il7r
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone: A7R34
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: P16872
Immunogen: Proprietary immunogen
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD127 (IL-7Ra)
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Il7r
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone:
A7R34
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
P16872
Immunogen:
Proprietary immunogen
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD161 (NK1.1)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Mouse
Research Discipline: Inflammation, Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone: PK136
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: __
Immunogen: Proprietary immunogen
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD161 (NK1.1)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Mouse
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone:
PK136
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
__
Immunogen:
Proprietary immunogen
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD161 (NK1.1)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Mouse
Research Discipline: Inflammation, Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone: PK136
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: __
Immunogen: Proprietary immunogen
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD161 (NK1.1)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Mouse
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone:
PK136
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
__
Immunogen:
Proprietary immunogen
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD161 (NK1.1)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Mouse
Research Discipline: Inflammation, Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone: PK136
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Accession No.: __
Immunogen: Proprietary immunogen
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD161 (NK1.1)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Mouse
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Clone:
PK136
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Accession No.:
__
Immunogen:
Proprietary immunogen
Purification Method:
Purified by size-exclusion chromatography