5349422
MilliporeSigma™ anti-CD161 (NK1.1) FITC, Clone: PK136,
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD161 (NK1.1)
Applications
Flow Cytometry
Conjugate
FITC
Host Species
Mouse
Research Discipline
Inflammation, Immunology
Formulation
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype
IgG2a κ
Purification Method
Purified by size-exclusion chromatography
Clone
PK136
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Immunogen
Proprietary immunogen
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Related Products
Description
- Specifically detects CD161 (NK1.1) Clone: PK136 in Mouse samples, and it is validated for Flow Cytometry The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family
- NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells
- NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129)
- Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al
- 2012
- Endocrinology
- 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB
- The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al
- 2006
- J
- Immunol
- 176: 7511-7524).
Compare Similar Items
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Antigen: CD161 (NK1.1)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Mouse
Research Discipline: Inflammation, Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype: IgG2a κ
Purification Method: Purified by size-exclusion chromatography
Clone: PK136
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
CD161 (NK1.1)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Mouse
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype:
IgG2a κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
PK136
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: IFN gamma
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype: IgG1 κ
Purification Method: Purified by size-exclusion chromatography
Clone: XMG1.2
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
IFN gamma
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype:
IgG1 κ
Purification Method:
Purified by size-exclusion chromatography
Clone:
XMG1.2
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: IL-2
Applications: Flow Cytometry
Conjugate: Biotin
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype: __
Purification Method: Purified by size-exclusion chromatography
Clone: JES6-5H4
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
IL-2
Applications:
Flow Cytometry
Conjugate:
Biotin
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype:
__
Purification Method:
Purified by size-exclusion chromatography
Clone:
JES6-5H4
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen: IL-2
Applications: Flow Cytometry
Conjugate: Biotin
Host Species: Rat
Research Discipline: Inflammation, Immunology
Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype: __
Purification Method: Purified by size-exclusion chromatography
Clone: JES6-5H4
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Proprietary immunogen
Primary or Secondary: Primary
Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Antigen:
IL-2
Applications:
Flow Cytometry
Conjugate:
Biotin
Host Species:
Rat
Research Discipline:
Inflammation, Immunology
Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Isotype:
__
Purification Method:
Purified by size-exclusion chromatography
Clone:
JES6-5H4
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Proprietary immunogen
Primary or Secondary:
Primary
Content And Storage:
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze