5349714

MilliporeSigma™ anti-Ly-6G, PE-Cy7, Clone: 1A8,

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Ly-6G

Applications

Flow Cytometry

Conjugate

PE-Cyanine7

Host Species

Rat

Research Discipline

Inflammation, Immunology

Formulation

Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols

Ly6g

Isotype

IgG2a κ

Purification Method

Purified by size-exclusion chromatography

Clone

1A8

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Mouse

Gene Accession No.

P35461

Immunogen

Proprietary immunogen

Primary or Secondary

Primary

Content And Storage

2°C to 8°C for one year from date of shipment protected from light; Do not freeze

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Description

  • Specifically detects Ly-6G Clone: 1A8 in Mouse samples, and it is validated for Flow Cytometry The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion
  • Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils
  • In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes
  • Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al
  • 1993
  • J
  • Immunol
  • 151: 2399-2408 and Sasmono et al
  • 2007
  • J
  • Leukoc
  • Biol
  • 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

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5349714

Rat Monoclonal Antibody...


Antigen:
Ly-6G

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Rat

Research Discipline:
Inflammation, Immunology

Formulation:
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols:
Ly6g

Isotype:
IgG2a κ

Purification Method:
Purified by size-exclusion chromatography

Clone:
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Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Mouse

Gene Accession No.:
P35461

Immunogen:
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Primary or Secondary:
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Gene Symbols:
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Isotype:
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Clone:
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RUO

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