5539123
beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
beta 2-Microglobulin
Concentration
0.2 mg/mL
Applications
Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols
B2M
Isotype
IgG2a κ
Purification Method
Protein A or G purified
Test Specificity
Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Clone
246-E9.E7 (same as HLA.ABC.m2)
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human, Primate (Negative)
Gene Accession No.
P61769
Gene ID (Entrez)
567
Immunogen
Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Molecular Weight of Antigen
12 kDa
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples
- It is validated for Flow Cytometry, Immunofluorescence.
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Antigen: beta 2-Microglobulin
Concentration: 0.2 mg/mL
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols: B2M
Isotype: IgG2a κ
Purification Method: Protein A or G purified
Test Specificity: Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Clone: 246-E9.E7 (same as HLA.ABC.m2)
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Primate (Negative)
Gene Accession No.: P61769
Gene ID (Entrez): 567
Immunogen: Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Molecular Weight of Antigen: 12 kDa
Antigen:
beta 2-Microglobulin
Concentration:
0.2 mg/mL
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols:
B2M
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Clone:
246-E9.E7 (same as HLA.ABC.m2)
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Primate (Negative)
Gene Accession No.:
P61769
Gene ID (Entrez):
567
Immunogen:
Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Molecular Weight of Antigen:
12 kDa
Antigen: beta 2-Microglobulin
Concentration: 0.2mg/mL
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols: B2M
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Clone: B2M/1118
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Primate
Gene Accession No.: P61769
Gene ID (Entrez): 567
Immunogen: Full length recombinant human B2M protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Molecular Weight of Antigen: 12 kDa
Antigen:
beta 2-Microglobulin
Concentration:
0.2mg/mL
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols:
B2M
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Clone:
B2M/1118
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Primate
Gene Accession No.:
P61769
Gene ID (Entrez):
567
Immunogen:
Full length recombinant human B2M protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Molecular Weight of Antigen:
12 kDa
Antigen: __
Concentration: __
Applications: __
Conjugate: __
Host Species: __
Research Discipline: __
Formulation: __
Gene Alias: __
Gene Symbols: __
Isotype: __
Purification Method: __
Test Specificity: __
Clone: __
Dilution: __
Classification: __
Form: __
Regulatory Status: __
Target Species: __
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Molecular Weight of Antigen: __
Antigen:
__
Concentration:
__
Applications:
__
Conjugate:
__
Host Species:
__
Research Discipline:
__
Formulation:
__
Gene Alias:
__
Gene Symbols:
__
Isotype:
__
Purification Method:
__
Test Specificity:
__
Clone:
__
Dilution:
__
Classification:
__
Form:
__
Regulatory Status:
__
Target Species:
__
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__
Molecular Weight of Antigen:
__
Antigen: beta-1,3-Glucuronyltransferase 1/B3GAT1
Concentration: 0.2mg/mL
Applications: Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer, Immunology
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: Beta-1,3-glucuronyltransferase 1, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P), EC 2.4.1.135, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, GlcAT-P, GLCATPGLCUATP, glcUAT-P, Glucuronosyltransferase P, NK1, NK-1, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
Gene Symbols: B3GAT1
Isotype: IgM
Purification Method: Protein A or G purified
Test Specificity: Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Clone: HNK-1 + NK-1
Dilution: Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Rat (Negative)
Gene Accession No.: Q9P2W7
Gene ID (Entrez): 27087
Immunogen: Human peripheral blood mononuclear cells (HNK-1 and NK-1)
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Molecular Weight of Antigen: __
Antigen:
beta-1,3-Glucuronyltransferase 1/B3GAT1
Concentration:
0.2mg/mL
Applications:
Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cancer, Immunology
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
Beta-1,3-glucuronyltransferase 1, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P), EC 2.4.1.135, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, GlcAT-P, GLCATPGLCUATP, glcUAT-P, Glucuronosyltransferase P, NK1, NK-1, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
Gene Symbols:
B3GAT1
Isotype:
IgM
Purification Method:
Protein A or G purified
Test Specificity:
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Clone:
HNK-1 + NK-1
Dilution:
Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat (Negative)
Gene Accession No.:
Q9P2W7
Gene ID (Entrez):
27087
Immunogen:
Human peripheral blood mononuclear cells (HNK-1 and NK-1)
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Molecular Weight of Antigen:
__