Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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CD2
0.2 mg/mL
Flow Cytometry, Immunofluorescence
Unconjugated
Mouse
Adaptive Immunity, Apoptosis, Immunology
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
CD2
IgG2b κ
Protein A or G purified
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
HuLy-m1
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
Human, Feline
P06729
914
Human thymocytes
Primary
Store at 4C.
50 kDa