5541003
TGF-alpha Antibody (TGFA/1119), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TGF-alpha
Concentration
0.2mg/mL
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Angiogenesis, Cell Cycle and Replication, Signal Transduction
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias
protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Gene Symbols
TGFA
Isotype
IgG1 κ
Purification Method
Protein A or G purified
Test Specificity
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Clone
TGFA/1119
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Accession No.
P01135
Gene ID (Entrez)
7039
Immunogen
Recombinant human full-length TGF alpha protein
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Related Products
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence TGF-alpha Monoclonal specifically detects TGF-alpha in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: TGF-alpha
Concentration: 0.2mg/mL
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Angiogenesis, Cell Cycle and Replication, Signal Transduction
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Gene Symbols: TGFA
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Clone: TGFA/1119
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P01135
Gene ID (Entrez): 7039
Immunogen: Recombinant human full-length TGF alpha protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
TGF-alpha
Concentration:
0.2mg/mL
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Angiogenesis, Cell Cycle and Replication, Signal Transduction
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Gene Symbols:
TGFA
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Clone:
TGFA/1119
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P01135
Gene ID (Entrez):
7039
Immunogen:
Recombinant human full-length TGF alpha protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Antigen: TGF-beta
Concentration: 0.2 mg/mL
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), ELISA
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: __
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: __
Gene Symbols: TGFB1
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
Clone: 1D11.16.8
Dilution: Immunocytochemistry/Immunofluorescence 8-25 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0ug/ml, Sandwich ELISA, ELISA Capture (Matched Antibody Pair)
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
Gene Accession No.: P10600, P61812
Gene ID (Entrez): 7040
Immunogen: Bovine TGF-beta2 protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
TGF-beta
Concentration:
0.2 mg/mL
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
__
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
__
Gene Symbols:
TGFB1
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
Clone:
1D11.16.8
Dilution:
Immunocytochemistry/Immunofluorescence 8-25 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0ug/ml, Sandwich ELISA, ELISA Capture (Matched Antibody Pair)
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
Gene Accession No.:
P10600, P61812
Gene ID (Entrez):
7040
Immunogen:
Bovine TGF-beta2 protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Antigen: TLR4
Concentration: 0.2 mg/mL
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Gene Symbols: TLR4
Isotype: IgG2a κ
Purification Method: Protein A or G purified
Test Specificity: This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clone: TLR4/230
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Rat, Porcine, Canine, Guinea Pig, Monkey
Gene Accession No.: O00206
Gene ID (Entrez): 7099
Immunogen: Recombinant human TLR4 protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
TLR4
Concentration:
0.2 mg/mL
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Gene Symbols:
TLR4
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clone:
TLR4/230
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat, Porcine, Canine, Guinea Pig, Monkey
Gene Accession No.:
O00206
Gene ID (Entrez):
7099
Immunogen:
Recombinant human TLR4 protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Antigen: TLR4
Concentration: 0.2 mg/mL
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Gene Symbols: TLR4
Isotype: IgG2a κ
Purification Method: Protein A or G purified
Test Specificity: This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clone: TLR4/230
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Rat, Porcine, Canine, Guinea Pig, Monkey
Gene Accession No.: O00206
Gene ID (Entrez): 7099
Immunogen: Recombinant human TLR4 protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
TLR4
Concentration:
0.2 mg/mL
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Gene Symbols:
TLR4
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clone:
TLR4/230
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat, Porcine, Canine, Guinea Pig, Monkey
Gene Accession No.:
O00206
Gene ID (Entrez):
7099
Immunogen:
Recombinant human TLR4 protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.