5539704

IGF-I/IGF-1 Antibody (IGF1/1020), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IGF-I

Concentration

0.2 mg/mL

Applications

Flow Cytometry, Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cell Cycle and Replication

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Gene Symbols

IGF1

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Clone

IGF1/1020

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse, Rat, Rabbit

Gene Accession No.

P05019

Gene ID (Entrez)

3479

Immunogen

Full-length recombinant human IGF-1 protein

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

7.6 kDa

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

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Fischer Scientific

5539704

Mouse Monoclonal Antibody...


Antigen:
IGF-I

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Gene Symbols:
IGF1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Clone:
IGF1/1020

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Rabbit

Gene Accession No.:
P05019

Gene ID (Entrez):
3479

Immunogen:
Full-length recombinant human IGF-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
7.6 kDa

Img

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5539736

Mouse Monoclonal Antibody...


Antigen:
Insulin

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Gene Symbols:
INS

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Clone:
IRDN/794

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.1 - 0.2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Porcine, Primate

Gene Accession No.:
P01308

Gene ID (Entrez):
3630

Immunogen:
Recombinant INS protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
6 kDa

Img

Fischer Scientific

5539736

Mouse Monoclonal Antibody...


Antigen:
Insulin

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Gene Symbols:
INS

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Clone:
IRDN/794

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.1 - 0.2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Porcine, Primate

Gene Accession No.:
P01308

Gene ID (Entrez):
3630

Immunogen:
Recombinant INS protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
6 kDa

Img

Fischer Scientific

5539737

Mouse Monoclonal Antibody...


Antigen:
Insulin

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Gene Symbols:
INS

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Clone:
IRDN/805

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Porcine, Primate, Rabbit, Rat (Negative)

Gene Accession No.:
P01308

Gene ID (Entrez):
3630

Immunogen:
Recombinant INS protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
6 kDa